The tumor suppressor LKB1 regulates starvation-induced autophagy under systemic metabolic stress

The tumor suppressor LKB1 regulates starvation-induced autophagy under systemic metabolic stress

Abstract Autophagy is an evolutionarily conserved process that degrades cellular components to restore energy homeostasis under limited nutrient conditions. How this starvation-induced autophagy is regulated at the whole-body level is not fully understood. Here, we show that the tumor suppressor Lkb...

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Autores principales: Laurie A. Mans, Laia Querol Cano, Jason van Pelt, Panagiota Giardoglou, Willem-Jan Keune, Anna-Pavlina G. Haramis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a9bb0a73063543c0bfdc9ea6d0b08b78
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