Conservative treatment for acute coronary syndrome in patients with type 2 diabetes mellitus

2 diabetes mellitus (T2DM). Dyspnea during physical exertion should be considered an anginal equivalent in patients with T2DM, and suffocation causing admission to ICU ? as a possible sign of myocardial infarction. Proximal and distal coronary lesions combined with diabetic microangiopathy compromis...

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Autores principales:	Sergey Valentinovich Kakorin, Lev Borisovich Kruglyi, Ashot Musaelovich Mkrtumyan
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2013
Materias:	type 2 diabetes mellitus acute coronary syndrome myocardial infarction thromobolytic anticoagulant antiplatelet antianginal beta blocker ace hmg-coa reductase inhibitor Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/a9c15a9d6c124cc49da00c703fdc88ba
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spelling	oai:doaj.org-article:a9c15a9d6c124cc49da00c703fdc88ba2021-11-14T09:00:18ZConservative treatment for acute coronary syndrome in patients with type 2 diabetes mellitus2072-03512072-037810.14341/2072-0351-3755https://doaj.org/article/a9c15a9d6c124cc49da00c703fdc88ba2013-06-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/3755https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-03782 diabetes mellitus (T2DM). Dyspnea during physical exertion should be considered an anginal equivalent in patients with T2DM, and suffocation causing admission to ICU ? as a possible sign of myocardial infarction. Proximal and distal coronary lesions combined with diabetic microangiopathy compromising collateral circulation are a frequent finding in these patients. Therefore an infusion of nitroglycerine may yield a rapid improvement in their condition. Treatment with low-molecular-weight heparin (LMWH) should be administered for a longer period due to rheological disturbances in T2DM. Diabetic patients with a history of myocardial infarction (MI) should receive a life-long therapeutic combination of two different antiplatelet agents. Carvedilol, a non-selective beta blocker/ alpha-1 blocker, and selective beta-1 blockers (e.g. nebivolol, bisoprolol) have better safety profile than other beta blockers concerning neurological aspects of hypoglycemic events.Sergey Valentinovich KakorinLev Borisovich KruglyiAshot Musaelovich MkrtumyanEndocrinology Research Centrearticletype 2 diabetes mellitusacute coronary syndromemyocardial infarctionthromobolyticanticoagulantantiplateletantianginalbeta blockeracehmg-coa reductase inhibitorNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 16, Iss 2, Pp 43-51 (2013)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	type 2 diabetes mellitus acute coronary syndrome myocardial infarction thromobolytic anticoagulant antiplatelet antianginal beta blocker ace hmg-coa reductase inhibitor Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	type 2 diabetes mellitus acute coronary syndrome myocardial infarction thromobolytic anticoagulant antiplatelet antianginal beta blocker ace hmg-coa reductase inhibitor Nutritional diseases. Deficiency diseases RC620-627 Sergey Valentinovich Kakorin Lev Borisovich Kruglyi Ashot Musaelovich Mkrtumyan Conservative treatment for acute coronary syndrome in patients with type 2 diabetes mellitus
description	2 diabetes mellitus (T2DM). Dyspnea during physical exertion should be considered an anginal equivalent in patients with T2DM, and suffocation causing admission to ICU ? as a possible sign of myocardial infarction. Proximal and distal coronary lesions combined with diabetic microangiopathy compromising collateral circulation are a frequent finding in these patients. Therefore an infusion of nitroglycerine may yield a rapid improvement in their condition. Treatment with low-molecular-weight heparin (LMWH) should be administered for a longer period due to rheological disturbances in T2DM. Diabetic patients with a history of myocardial infarction (MI) should receive a life-long therapeutic combination of two different antiplatelet agents. Carvedilol, a non-selective beta blocker/ alpha-1 blocker, and selective beta-1 blockers (e.g. nebivolol, bisoprolol) have better safety profile than other beta blockers concerning neurological aspects of hypoglycemic events.
format	article
author	Sergey Valentinovich Kakorin Lev Borisovich Kruglyi Ashot Musaelovich Mkrtumyan
author_facet	Sergey Valentinovich Kakorin Lev Borisovich Kruglyi Ashot Musaelovich Mkrtumyan
author_sort	Sergey Valentinovich Kakorin
title	Conservative treatment for acute coronary syndrome in patients with type 2 diabetes mellitus
title_short	Conservative treatment for acute coronary syndrome in patients with type 2 diabetes mellitus
title_full	Conservative treatment for acute coronary syndrome in patients with type 2 diabetes mellitus
title_fullStr	Conservative treatment for acute coronary syndrome in patients with type 2 diabetes mellitus
title_full_unstemmed	Conservative treatment for acute coronary syndrome in patients with type 2 diabetes mellitus
title_sort	conservative treatment for acute coronary syndrome in patients with type 2 diabetes mellitus
publisher	Endocrinology Research Centre
publishDate	2013
url	https://doaj.org/article/a9c15a9d6c124cc49da00c703fdc88ba
work_keys_str_mv	AT sergeyvalentinovichkakorin conservativetreatmentforacutecoronarysyndromeinpatientswithtype2diabetesmellitus AT levborisovichkruglyi conservativetreatmentforacutecoronarysyndromeinpatientswithtype2diabetesmellitus AT ashotmusaelovichmkrtumyan conservativetreatmentforacutecoronarysyndromeinpatientswithtype2diabetesmellitus
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Conservative treatment for acute coronary syndrome in patients with type 2 diabetes mellitus

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