AIB1 cooperates with ERα to promote epithelial mesenchymal transition in breast cancer through SNAI1 activation.

AIB1 cooperates with ERα to promote epithelial mesenchymal transition in breast cancer through SNAI1 activation.

Epithelial Mesenchymal Transition (EMT) plays a major role in cancer metastasis. Several genes have been shown to play a role in EMT, and one of these is Amplified-in-breast cancer 1 (AIB1), which has oncogenic function and is known to be amplified in breast cancer. However, the role of AIB1 in EMT...

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Main Authors: Miao Wang, Feng Zhao, Shujing Li, Alan K Chang, Zhaojun Jia, Yixuan Chen, Feihong Xu, Hongming Pan, Huijian Wu
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/a9c23c38cf304d12bf62d0fe1febb3af
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