Molecular evidence of functional progesterone withdrawal in human myometrium
How human labour is initiated in the presence of high circulating progesterone is still unclear. Here, the authors show that during a reduction in myometrial nuclear progesterone levels, there is an increased transcription of the key labour gene, Cx43, mediated by unliganded progesterone receptor A.
Guardado en:
Autores principales: | Lubna Nadeem, Oksana Shynlova, Elzbieta Matysiak-Zablocki, Sam Mesiano, Xuesen Dong, Stephen Lye |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/a9cbb860df8546a38946568c449db560 |
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