Risk Factors for Malnutrition among IBD Patients

(1) Background: Malnutrition is a highly prevalent complication in patients with inflammatory bowel diseases (IBD). It is strongly associated with poor clinical outcomes and quality of life. Screening for malnutrition risk is recommended routinely; however, current malnutrition screening tools do no...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Larisa Einav, Ayal Hirsch, Yulia Ron, Nathaniel Aviv Cohen, Sigalit Lahav, Jasmine Kornblum, Ronit Anbar, Nitsan Maharshak, Naomi Fliss-Isakov
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	malnutrition screening inflammatory bowel disease Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/a9d65106a91d442c944a4cfebe45c1cc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a9d65106a91d442c944a4cfebe45c1cc
record_format	dspace
spelling	oai:doaj.org-article:a9d65106a91d442c944a4cfebe45c1cc2021-11-25T18:36:44ZRisk Factors for Malnutrition among IBD Patients10.3390/nu131140982072-6643https://doaj.org/article/a9d65106a91d442c944a4cfebe45c1cc2021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/4098https://doaj.org/toc/2072-6643(1) Background: Malnutrition is a highly prevalent complication in patients with inflammatory bowel diseases (IBD). It is strongly associated with poor clinical outcomes and quality of life. Screening for malnutrition risk is recommended routinely; however, current malnutrition screening tools do not incorporate IBD specific characteristics and may be less adequate for screening these patients. Therefore, we aimed to identify IBD-related risk factors for development of malnutrition. (2) Methods: A retrospective case-control study among IBD patients attending the IBD clinic of the Tel-Aviv Medical Center for ≥2 consecutive physician consultations per year during 2017–2020. Cases who had normal nutritional status and developed malnutrition between visits were compared to matched controls who maintained normal nutritional status. Detailed information was gathered from medical files, including: demographics, disease phenotype, characteristics and activity, diet altering symptoms and comorbidities, medical and surgical history, annual healthcare utility, nutritional intake and the Malnutrition Universal Screening Tool (MUST) score. Univariate and multivariate analyses were used to identify malnutrition risk factors. The independent risk factors identified were summed up to calculate the IBD malnutrition risk score (IBD-MR). (3) Results: Data of 1596 IBD patients met the initial criteria for the study. Of these, 59 patients developed malnutrition and were defined as cases (<i>n</i> = 59) and matched to controls (<i>n</i> = 59). The interval between the physician consultations was 6.2 ± 3.0 months, during which cases lost 5.3 ± 2.3 kg of body weight and controls gained 0.2 ± 2.3 kg (<i>p</i> < 0.001). Cases and controls did not differ in demographics, disease duration, disease phenotype or medical history. Independent IBD-related malnutrition risk factors were: 18.5 ≤ BMI ≤ 22 kg/m<sup>2</sup> (OR = 4.71, 95%CI 1.13–19.54), high annual healthcare utility (OR = 5.67, 95%CI 1.02–31.30) and endoscopic disease activity (OR = 5.49, 95%CI 1.28–23.56). The IBD-MR was positively associated with malnutrition development independently of the MUST score (OR = 7.39, 95%CI 2.60–20.94). Among patients with low MUST scores determined during the index visit, identification of ≥2 IBD-MR factors was strongly associated with malnutrition development (OR = 8.65, 95%CI 2.21–33.82, <i>p</i> = 0.002). (4) Conclusions: We identified IBD-related risk factors for malnutrition, highlighting the need for a disease-specific malnutrition screening tool, which may increase malnutrition risk detection.Larisa EinavAyal HirschYulia RonNathaniel Aviv CohenSigalit LahavJasmine KornblumRonit AnbarNitsan MaharshakNaomi Fliss-IsakovMDPI AGarticlemalnutritionscreeninginflammatory bowel diseaseNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 4098, p 4098 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	malnutrition screening inflammatory bowel disease Nutrition. Foods and food supply TX341-641
spellingShingle	malnutrition screening inflammatory bowel disease Nutrition. Foods and food supply TX341-641 Larisa Einav Ayal Hirsch Yulia Ron Nathaniel Aviv Cohen Sigalit Lahav Jasmine Kornblum Ronit Anbar Nitsan Maharshak Naomi Fliss-Isakov Risk Factors for Malnutrition among IBD Patients
description	(1) Background: Malnutrition is a highly prevalent complication in patients with inflammatory bowel diseases (IBD). It is strongly associated with poor clinical outcomes and quality of life. Screening for malnutrition risk is recommended routinely; however, current malnutrition screening tools do not incorporate IBD specific characteristics and may be less adequate for screening these patients. Therefore, we aimed to identify IBD-related risk factors for development of malnutrition. (2) Methods: A retrospective case-control study among IBD patients attending the IBD clinic of the Tel-Aviv Medical Center for ≥2 consecutive physician consultations per year during 2017–2020. Cases who had normal nutritional status and developed malnutrition between visits were compared to matched controls who maintained normal nutritional status. Detailed information was gathered from medical files, including: demographics, disease phenotype, characteristics and activity, diet altering symptoms and comorbidities, medical and surgical history, annual healthcare utility, nutritional intake and the Malnutrition Universal Screening Tool (MUST) score. Univariate and multivariate analyses were used to identify malnutrition risk factors. The independent risk factors identified were summed up to calculate the IBD malnutrition risk score (IBD-MR). (3) Results: Data of 1596 IBD patients met the initial criteria for the study. Of these, 59 patients developed malnutrition and were defined as cases (<i>n</i> = 59) and matched to controls (<i>n</i> = 59). The interval between the physician consultations was 6.2 ± 3.0 months, during which cases lost 5.3 ± 2.3 kg of body weight and controls gained 0.2 ± 2.3 kg (<i>p</i> < 0.001). Cases and controls did not differ in demographics, disease duration, disease phenotype or medical history. Independent IBD-related malnutrition risk factors were: 18.5 ≤ BMI ≤ 22 kg/m<sup>2</sup> (OR = 4.71, 95%CI 1.13–19.54), high annual healthcare utility (OR = 5.67, 95%CI 1.02–31.30) and endoscopic disease activity (OR = 5.49, 95%CI 1.28–23.56). The IBD-MR was positively associated with malnutrition development independently of the MUST score (OR = 7.39, 95%CI 2.60–20.94). Among patients with low MUST scores determined during the index visit, identification of ≥2 IBD-MR factors was strongly associated with malnutrition development (OR = 8.65, 95%CI 2.21–33.82, <i>p</i> = 0.002). (4) Conclusions: We identified IBD-related risk factors for malnutrition, highlighting the need for a disease-specific malnutrition screening tool, which may increase malnutrition risk detection.
format	article
author	Larisa Einav Ayal Hirsch Yulia Ron Nathaniel Aviv Cohen Sigalit Lahav Jasmine Kornblum Ronit Anbar Nitsan Maharshak Naomi Fliss-Isakov
author_facet	Larisa Einav Ayal Hirsch Yulia Ron Nathaniel Aviv Cohen Sigalit Lahav Jasmine Kornblum Ronit Anbar Nitsan Maharshak Naomi Fliss-Isakov
author_sort	Larisa Einav
title	Risk Factors for Malnutrition among IBD Patients
title_short	Risk Factors for Malnutrition among IBD Patients
title_full	Risk Factors for Malnutrition among IBD Patients
title_fullStr	Risk Factors for Malnutrition among IBD Patients
title_full_unstemmed	Risk Factors for Malnutrition among IBD Patients
title_sort	risk factors for malnutrition among ibd patients
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/a9d65106a91d442c944a4cfebe45c1cc
work_keys_str_mv	AT larisaeinav riskfactorsformalnutritionamongibdpatients AT ayalhirsch riskfactorsformalnutritionamongibdpatients AT yuliaron riskfactorsformalnutritionamongibdpatients AT nathanielavivcohen riskfactorsformalnutritionamongibdpatients AT sigalitlahav riskfactorsformalnutritionamongibdpatients AT jasminekornblum riskfactorsformalnutritionamongibdpatients AT ronitanbar riskfactorsformalnutritionamongibdpatients AT nitsanmaharshak riskfactorsformalnutritionamongibdpatients AT naomiflissisakov riskfactorsformalnutritionamongibdpatients
_version_	1718410910295392256

Risk Factors for Malnutrition among IBD Patients

Ejemplares similares