Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR).
Bacterial populations co-ordinate gene expression collectively through quorum sensing (QS), a cell-to-cell communication mechanism employing diffusible signal molecules. The LysR-type transcriptional regulator (LTTR) protein PqsR (MvfR) is a key component of alkyl-quinolone (AQ)-dependent QS in Pseu...
Guardado en:
Autores principales: | Aravindan Ilangovan, Matthew Fletcher, Giordano Rampioni, Christian Pustelny, Kendra Rumbaugh, Stephan Heeb, Miguel Cámara, Alex Truman, Siri Ram Chhabra, Jonas Emsley, Paul Williams |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
|
Materias: | |
Acceso en línea: | https://doaj.org/article/a9d92550d45d4a6c855756a389e861cf |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Molecular Insights into Binding Mode and Interactions of Structure-Based Virtually Screened Inhibitors for <i>Pseudomonas aeruginosa</i> Multiple Virulence Factor Regulator (MvfR)
por: Raed A. H. Almihyawi, et al.
Publicado: (2021) -
Identification of FDA-approved antivirulence drugs targeting the Pseudomonas aeruginosa quorum sensing effector protein PqsE
por: Valerio Baldelli, et al.
Publicado: (2020) -
PqsE Is Essential for RhlR-Dependent Quorum Sensing Regulation in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>
por: Marie-Christine Groleau, et al.
Publicado: (2020) -
Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through lack of the Rieske cytochrome bc1 sub-unit.
por: Eliza Ye-Chen Soh, et al.
Publicado: (2021) -
Engineering PQS biosynthesis pathway for enhancement of bioelectricity production in pseudomonas aeruginosa microbial fuel cells.
por: Victor Bochuan Wang, et al.
Publicado: (2013)