PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions.

PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions.

G protein-coupled receptors (GPCRs) constitute the largest family of membrane proteins in the human genome. Their signaling is regulated by scaffold proteins containing PDZ domains, but although these interactions are important for GPCR function, they are still poorly understood. We here present a q...

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Autores principales: Thor C Møller, Volker F Wirth, Nina I Roberts, Julia Bender, Anders Bach, Birgitte P S Jacky, Kristian Strømgaard, Jan M Deussing, Thue W Schwartz, Karen L Martinez
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a9defa479cb94c259cea6884cc9f692f
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