Variants in the 15q24/25 locus associate with lung function decline in active smokers.

Variants in the 15q24/25 locus associate with lung function decline in active smokers.

Genetic variation in nicotinic acetylcholine receptor subunit genes (nAChRs) is associated with lung function level and chronic obstructive pulmonary disease (COPD). It is unknown whether these variants also predispose to an accelerated lung function decline. We investigated the association of nAChR...

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Autores principales: Firdaus A A Mohamed Hoesein, Els Wauters, Wim Janssens, Harry J M Groen, Joanna Smolonska, Cisca Wijmenga, Dirkje S Postma, H Marike Boezen, Pim A De Jong, Marc Decramer, Jan-Willem J Lammers, Diether Lambrechts, Pieter Zanen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a9e120c027844384973e9562aa39e062
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