ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling

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ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling

ADNP has been connected to neural developmental disorders. Here, the authors uncover a role for ADNP in neural induction and differentiation via β-Catenin stabilization, with ADNP disruption in zebrafish leading to defective neurogenesis and decreased Wnt signaling.

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Detalles Bibliográficos
Autores principales:	Xiaoyun Sun, Xixia Peng, Yuqin Cao, Yan Zhou, Yuhua Sun
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a9e1314be5cb408b847ffc95329b794a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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