ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling
ADNP has been connected to neural developmental disorders. Here, the authors uncover a role for ADNP in neural induction and differentiation via β-Catenin stabilization, with ADNP disruption in zebrafish leading to defective neurogenesis and decreased Wnt signaling.
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Main Authors: | Xiaoyun Sun, Xixia Peng, Yuqin Cao, Yan Zhou, Yuhua Sun |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Subjects: | |
Online Access: | https://doaj.org/article/a9e1314be5cb408b847ffc95329b794a |
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