ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling

ADNP has been connected to neural developmental disorders. Here, the authors uncover a role for ADNP in neural induction and differentiation via β-Catenin stabilization, with ADNP disruption in zebrafish leading to defective neurogenesis and decreased Wnt signaling.

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Bibliographic Details
Main Authors: Xiaoyun Sun, Xixia Peng, Yuqin Cao, Yan Zhou, Yuhua Sun
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
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Online Access:https://doaj.org/article/a9e1314be5cb408b847ffc95329b794a
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