Room air constituent concentrations from use of electronic nicotine delivery systems and cigarettes using different ventilation conditions

Abstract To assess potential exposure of non-users to exhaled constituents from pod and cartridge electronic nicotine delivery systems (ENDS) products, an environmental clinical study was conducted with (n = 43) healthy adult smokers. Room air concentrations of 34 selected constituents (nicotine, pr...

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Autores principales: Michael J. Oldham, Anil Sehgal, Gal Cohen, Joey Chen, Blair Evans, Daniel Heraldez
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a9ebb37e81be4ed89bded521f06449be
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spelling oai:doaj.org-article:a9ebb37e81be4ed89bded521f06449be2021-12-02T15:23:38ZRoom air constituent concentrations from use of electronic nicotine delivery systems and cigarettes using different ventilation conditions10.1038/s41598-021-80963-92045-2322https://doaj.org/article/a9ebb37e81be4ed89bded521f06449be2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-80963-9https://doaj.org/toc/2045-2322Abstract To assess potential exposure of non-users to exhaled constituents from pod and cartridge electronic nicotine delivery systems (ENDS) products, an environmental clinical study was conducted with (n = 43) healthy adult smokers. Room air concentrations of 34 selected constituents (nicotine, propylene glycol, glycerin, 15 carbonyls, 12 volatile organic compounds, and 4 trace metals) and particle number concentration (0.3 to 25 µm) were compared from use of two ENDS products and conventional cigarettes using room ventilations representative of a residential, an office or a hospitality setting over a 4-h. exposure period. Products used were JUUL ENDS, Virginia Tobacco flavor (Group I), VUSE Solo, Original flavor (Group II) (5.0 and 4.8% nicotine by weight, respectively) and subjects’ own conventional cigarettes (Group III). Cumulative 4-h room air sampling and particle counting were performed during prescribed (Groups I and II) and ad libitum product use (all Groups). Conventional cigarette use resulted in significantly more constituents detected and higher 4-h cumulative constituent concentrations compared to use of the ENDS products tested, except for the predominant ENDS ingredients, propylene glycol and glycerin. Use of conventional cigarettes also resulted in greater total particle number concentration than either prescribed or ad libitum use of either of the ENDS used in this study.Michael J. OldhamAnil SehgalGal CohenJoey ChenBlair EvansDaniel HeraldezNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Michael J. Oldham
Anil Sehgal
Gal Cohen
Joey Chen
Blair Evans
Daniel Heraldez
Room air constituent concentrations from use of electronic nicotine delivery systems and cigarettes using different ventilation conditions
description Abstract To assess potential exposure of non-users to exhaled constituents from pod and cartridge electronic nicotine delivery systems (ENDS) products, an environmental clinical study was conducted with (n = 43) healthy adult smokers. Room air concentrations of 34 selected constituents (nicotine, propylene glycol, glycerin, 15 carbonyls, 12 volatile organic compounds, and 4 trace metals) and particle number concentration (0.3 to 25 µm) were compared from use of two ENDS products and conventional cigarettes using room ventilations representative of a residential, an office or a hospitality setting over a 4-h. exposure period. Products used were JUUL ENDS, Virginia Tobacco flavor (Group I), VUSE Solo, Original flavor (Group II) (5.0 and 4.8% nicotine by weight, respectively) and subjects’ own conventional cigarettes (Group III). Cumulative 4-h room air sampling and particle counting were performed during prescribed (Groups I and II) and ad libitum product use (all Groups). Conventional cigarette use resulted in significantly more constituents detected and higher 4-h cumulative constituent concentrations compared to use of the ENDS products tested, except for the predominant ENDS ingredients, propylene glycol and glycerin. Use of conventional cigarettes also resulted in greater total particle number concentration than either prescribed or ad libitum use of either of the ENDS used in this study.
format article
author Michael J. Oldham
Anil Sehgal
Gal Cohen
Joey Chen
Blair Evans
Daniel Heraldez
author_facet Michael J. Oldham
Anil Sehgal
Gal Cohen
Joey Chen
Blair Evans
Daniel Heraldez
author_sort Michael J. Oldham
title Room air constituent concentrations from use of electronic nicotine delivery systems and cigarettes using different ventilation conditions
title_short Room air constituent concentrations from use of electronic nicotine delivery systems and cigarettes using different ventilation conditions
title_full Room air constituent concentrations from use of electronic nicotine delivery systems and cigarettes using different ventilation conditions
title_fullStr Room air constituent concentrations from use of electronic nicotine delivery systems and cigarettes using different ventilation conditions
title_full_unstemmed Room air constituent concentrations from use of electronic nicotine delivery systems and cigarettes using different ventilation conditions
title_sort room air constituent concentrations from use of electronic nicotine delivery systems and cigarettes using different ventilation conditions
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a9ebb37e81be4ed89bded521f06449be
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