A CD8+ NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis
A better understanding of how multiple sclerosis (MS) can relapse and remit is needed for the identification of biomarkers and better therapeutics. Here the authors identify a CD8 + NK cell population in patients with relapsing remitting MS and validate its association with clinical outcome.
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Nature Portfolio
2021
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oai:doaj.org-article:a9f8d3a2bb3e4843b96a53187d7c017b2021-12-02T14:16:14ZA CD8+ NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis10.1038/s41467-020-20594-22041-1723https://doaj.org/article/a9f8d3a2bb3e4843b96a53187d7c017b2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20594-2https://doaj.org/toc/2041-1723A better understanding of how multiple sclerosis (MS) can relapse and remit is needed for the identification of biomarkers and better therapeutics. Here the authors identify a CD8 + NK cell population in patients with relapsing remitting MS and validate its association with clinical outcome.Eoin F. McKinneyIona CuthbertsonKristina M. HarrisDawn E. SmilekChristopher ConnorGiulia ManferrariEdward J. CarrScott S. ZamvilKenneth G. C. SmithNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021) |
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DOAJ |
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DOAJ |
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EN |
| topic |
Science Q |
| spellingShingle |
Science Q Eoin F. McKinney Iona Cuthbertson Kristina M. Harris Dawn E. Smilek Christopher Connor Giulia Manferrari Edward J. Carr Scott S. Zamvil Kenneth G. C. Smith A CD8+ NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis |
| description |
A better understanding of how multiple sclerosis (MS) can relapse and remit is needed for the identification of biomarkers and better therapeutics. Here the authors identify a CD8 + NK cell population in patients with relapsing remitting MS and validate its association with clinical outcome. |
| format |
article |
| author |
Eoin F. McKinney Iona Cuthbertson Kristina M. Harris Dawn E. Smilek Christopher Connor Giulia Manferrari Edward J. Carr Scott S. Zamvil Kenneth G. C. Smith |
| author_facet |
Eoin F. McKinney Iona Cuthbertson Kristina M. Harris Dawn E. Smilek Christopher Connor Giulia Manferrari Edward J. Carr Scott S. Zamvil Kenneth G. C. Smith |
| author_sort |
Eoin F. McKinney |
| title |
A CD8+ NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis |
| title_short |
A CD8+ NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis |
| title_full |
A CD8+ NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis |
| title_fullStr |
A CD8+ NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis |
| title_full_unstemmed |
A CD8+ NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis |
| title_sort |
cd8+ nk cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/a9f8d3a2bb3e4843b96a53187d7c017b |
| work_keys_str_mv |
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1718391685087494144 |