Tuberculosis epidemiological trend in Sousse, Tunisia during twenty years (2000–2019)

Describe the epidemiology of tuberculosis in the last two decades (2000–2019) in the East region of Tunisia (city of Sousse). This was a descriptive retrospective analysis of notified incident cases of tuberculosis from 2000 to 2019 in Sousse Governorate, Tunisia. The data collection was done via th...

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Autores principales:	Sarra Melki, Ghodhbani Mizouni, Dhekra Chebil, Ahmed Ben Abdelaziz
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2022
Materias:	tuberculosis epidemiology incidence mortality tunisia Medicine R
Acceso en línea:	https://doaj.org/article/aa026974a16c48b888acc7adf99a0483
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spelling	oai:doaj.org-article:aa026974a16c48b888acc7adf99a04832021-11-26T11:19:48ZTuberculosis epidemiological trend in Sousse, Tunisia during twenty years (2000–2019)1993-28201819-635710.1080/19932820.2021.2003968https://doaj.org/article/aa026974a16c48b888acc7adf99a04832022-01-01T00:00:00Zhttp://dx.doi.org/10.1080/19932820.2021.2003968https://doaj.org/toc/1993-2820https://doaj.org/toc/1819-6357Describe the epidemiology of tuberculosis in the last two decades (2000–2019) in the East region of Tunisia (city of Sousse). This was a descriptive retrospective analysis of notified incident cases of tuberculosis from 2000 to 2019 in Sousse Governorate, Tunisia. The data collection was done via the regional registry of tuberculosis. Stata software was used to characterize the socio-demographic and clinical profile of tuberculosis, to calculate its incidence, mortality and fatality rates and to determine predictive factors of mortality. R software was used to analyze the chronological trend of tuberculosis incidence and mortality. A total of 2606 incident cases of tuberculosis were declared from 2000 to 2019 in Sousse. The mean age was 39 ± 19 years with a sex ratio (male/female) of 1.19. Only one case was HIV positive among the total 2606 incident cases. Extra-pulmonary tuberculosis was the most recorded (1,534 cases, 58.9%). The mean annual case notification and deaths were 130 and four respectively. After adjusting for confounders, individuals with pulmonary tuberculosis were 1.9 significantly more likely to die from tuberculosis compared to those suffering from extra-pulmonary tuberculosis. There was a trend of increasing mortality with increasing age. The association was statistically significant only for those above 60 years’ old who had 12.5 times higher odds of dying compared to those below 60 years. After adjusting for age and gender, with every year there was an increase in the total incidence rate (+0.35 per 100,000) with p = 0.005 and in the extra-pulmonary incidence (+0.27 per 100,000), with p = 0.001. This study demonstrated the increasing trend of tuberculosis in Sousse, Tunisia from 2000 to 2019. The national program against tuberculosis should enhance community knowledge and centralize the national and regional epidemiological information for better epidemiological surveillance.Sarra MelkiGhodhbani MizouniDhekra ChebilAhmed Ben AbdelazizTaylor & Francis GrouparticletuberculosisepidemiologyincidencemortalitytunisiaMedicineRENLibyan Journal of Medicine, Vol 17, Iss 1 (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	tuberculosis epidemiology incidence mortality tunisia Medicine R
spellingShingle	tuberculosis epidemiology incidence mortality tunisia Medicine R Sarra Melki Ghodhbani Mizouni Dhekra Chebil Ahmed Ben Abdelaziz Tuberculosis epidemiological trend in Sousse, Tunisia during twenty years (2000–2019)
description	Describe the epidemiology of tuberculosis in the last two decades (2000–2019) in the East region of Tunisia (city of Sousse). This was a descriptive retrospective analysis of notified incident cases of tuberculosis from 2000 to 2019 in Sousse Governorate, Tunisia. The data collection was done via the regional registry of tuberculosis. Stata software was used to characterize the socio-demographic and clinical profile of tuberculosis, to calculate its incidence, mortality and fatality rates and to determine predictive factors of mortality. R software was used to analyze the chronological trend of tuberculosis incidence and mortality. A total of 2606 incident cases of tuberculosis were declared from 2000 to 2019 in Sousse. The mean age was 39 ± 19 years with a sex ratio (male/female) of 1.19. Only one case was HIV positive among the total 2606 incident cases. Extra-pulmonary tuberculosis was the most recorded (1,534 cases, 58.9%). The mean annual case notification and deaths were 130 and four respectively. After adjusting for confounders, individuals with pulmonary tuberculosis were 1.9 significantly more likely to die from tuberculosis compared to those suffering from extra-pulmonary tuberculosis. There was a trend of increasing mortality with increasing age. The association was statistically significant only for those above 60 years’ old who had 12.5 times higher odds of dying compared to those below 60 years. After adjusting for age and gender, with every year there was an increase in the total incidence rate (+0.35 per 100,000) with p = 0.005 and in the extra-pulmonary incidence (+0.27 per 100,000), with p = 0.001. This study demonstrated the increasing trend of tuberculosis in Sousse, Tunisia from 2000 to 2019. The national program against tuberculosis should enhance community knowledge and centralize the national and regional epidemiological information for better epidemiological surveillance.
format	article
author	Sarra Melki Ghodhbani Mizouni Dhekra Chebil Ahmed Ben Abdelaziz
author_facet	Sarra Melki Ghodhbani Mizouni Dhekra Chebil Ahmed Ben Abdelaziz
author_sort	Sarra Melki
title	Tuberculosis epidemiological trend in Sousse, Tunisia during twenty years (2000–2019)
title_short	Tuberculosis epidemiological trend in Sousse, Tunisia during twenty years (2000–2019)
title_full	Tuberculosis epidemiological trend in Sousse, Tunisia during twenty years (2000–2019)
title_fullStr	Tuberculosis epidemiological trend in Sousse, Tunisia during twenty years (2000–2019)
title_full_unstemmed	Tuberculosis epidemiological trend in Sousse, Tunisia during twenty years (2000–2019)
title_sort	tuberculosis epidemiological trend in sousse, tunisia during twenty years (2000–2019)
publisher	Taylor & Francis Group
publishDate	2022
url	https://doaj.org/article/aa026974a16c48b888acc7adf99a0483
work_keys_str_mv	AT sarramelki tuberculosisepidemiologicaltrendinsoussetunisiaduringtwentyyears20002019 AT ghodhbanimizouni tuberculosisepidemiologicaltrendinsoussetunisiaduringtwentyyears20002019 AT dhekrachebil tuberculosisepidemiologicaltrendinsoussetunisiaduringtwentyyears20002019 AT ahmedbenabdelaziz tuberculosisepidemiologicaltrendinsoussetunisiaduringtwentyyears20002019
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Tuberculosis epidemiological trend in Sousse, Tunisia during twenty years (2000–2019)

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