Dietary Intake of 17α-Ethinylestradiol Promotes HCC Progression in Humanized Male Mice Expressing Sex Hormone-Binding Globulin

Hepatocellular carcinoma (HCC) is a male-oriented malignancy; its progression is affected by sex hormones. 17α-ethinylestradiol (EE2) is a synthetic estrogen widely used as an oral contraceptive; however, it is unknown whether EE2 regulates sex hormone action in HCC. We investigated whether EE2 infl...

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Auteurs principaux: Sang R. Lee, Su Hee Jeong, Jun H. Heo, Seong Lae Jo, Je-Won Ko, Hyo-Jung Kwun, Eui-Ju Hong
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
HCC
EE2
Accès en ligne:https://doaj.org/article/aa028bec0f91437980d2cbfdf1b58801
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