AAV2-mediated subretinal gene transfer of hIFN-α attenuates experimental autoimmune uveoretinitis in mice.

<h4>Background</h4>Recent reports show that gene therapy may provide a long-term, safe and effective intervention for human diseases. In this study, we investigated the effectiveness of adeno-associated virus 2 (AAV2) based human interferon-alpha (hIFN-α) gene therapy in experimental aut...

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Autores principales: Lichun Tian, Peizeng Yang, Bo Lei, Ju Shao, Chaokui Wang, Qin Xiang, Lin Wei, Zhougui Peng, Aize Kijlstra
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/aa02fc6b890a4c099b44e472ad781bbc
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