AAV2-mediated subretinal gene transfer of hIFN-α attenuates experimental autoimmune uveoretinitis in mice.
<h4>Background</h4>Recent reports show that gene therapy may provide a long-term, safe and effective intervention for human diseases. In this study, we investigated the effectiveness of adeno-associated virus 2 (AAV2) based human interferon-alpha (hIFN-α) gene therapy in experimental aut...
Guardado en:
Autores principales: | Lichun Tian, Peizeng Yang, Bo Lei, Ju Shao, Chaokui Wang, Qin Xiang, Lin Wei, Zhougui Peng, Aize Kijlstra |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
|
Materias: | |
Acceso en línea: | https://doaj.org/article/aa02fc6b890a4c099b44e472ad781bbc |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The implications of subretinal fluid in pachychoroid neovasculopathy
por: Geun Woo Lee, et al.
Publicado: (2021) -
Subretinal angiostrongyliasis-induced optic neuritis
por: Sinawat S, et al.
Publicado: (2013) -
Genetic variations of IL-12B, IL-12Rβ1, IL-12Rβ2 in Behcet's disease and VKH syndrome.
por: Xinyu Li, et al.
Publicado: (2014) -
Long-term efficacy and safety of infliximab and cyclosporine combination therapy for refractory uveoretinitis in Behçet’s disease
por: Katsuyama A, et al.
Publicado: (2019) -
IFN-γ signaling to astrocytes protects from autoimmune mediated neurological disability.
por: Claudia Hindinger, et al.
Publicado: (2012)