AAV2-mediated subretinal gene transfer of hIFN-α attenuates experimental autoimmune uveoretinitis in mice.
<h4>Background</h4>Recent reports show that gene therapy may provide a long-term, safe and effective intervention for human diseases. In this study, we investigated the effectiveness of adeno-associated virus 2 (AAV2) based human interferon-alpha (hIFN-α) gene therapy in experimental aut...
Enregistré dans:
Auteurs principaux: | Lichun Tian, Peizeng Yang, Bo Lei, Ju Shao, Chaokui Wang, Qin Xiang, Lin Wei, Zhougui Peng, Aize Kijlstra |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/aa02fc6b890a4c099b44e472ad781bbc |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
The implications of subretinal fluid in pachychoroid neovasculopathy
par: Geun Woo Lee, et autres
Publié: (2021) -
Subretinal angiostrongyliasis-induced optic neuritis
par: Sinawat S, et autres
Publié: (2013) -
Genetic variations of IL-12B, IL-12Rβ1, IL-12Rβ2 in Behcet's disease and VKH syndrome.
par: Xinyu Li, et autres
Publié: (2014) -
Long-term efficacy and safety of infliximab and cyclosporine combination therapy for refractory uveoretinitis in Behçet’s disease
par: Katsuyama A, et autres
Publié: (2019) -
IFN-γ signaling to astrocytes protects from autoimmune mediated neurological disability.
par: Claudia Hindinger, et autres
Publié: (2012)