Variant surface glycoprotein density defines an immune evasion threshold for African trypanosomes undergoing antigenic variation
Trypanosoma brucei evades the host immune system through replacement of a variant surface glycoprotein (VSG) coat. Here, the authors show that VSG replacement takes several days to complete, and the parasite is vulnerable to the host immune system for a short period of time during the process.
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Autores principales: | Jason Pinger, Shanin Chowdhury, F. Nina Papavasiliou |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/aa06b14acc704be0b85627d28f67eda1 |
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