Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation
Prereplicative complex (pre-RC) formation during G1 is fundamental for cell replication. Here the authors report a role for cyclin K in regulating pre-RC formation in mammalian cells by affecting cyclin E1 activity.
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Nature Portfolio
2018
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oai:doaj.org-article:aa0bfdb189444623bd43e33efbfa2ec82021-12-02T16:49:23ZCyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation10.1038/s41467-018-04258-w2041-1723https://doaj.org/article/aa0bfdb189444623bd43e33efbfa2ec82018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04258-whttps://doaj.org/toc/2041-1723Prereplicative complex (pre-RC) formation during G1 is fundamental for cell replication. Here the authors report a role for cyclin K in regulating pre-RC formation in mammalian cells by affecting cyclin E1 activity.Tingjun LeiPeixuan ZhangXudong ZhangXue XiaoJingli ZhangTong QiuQian DaiYujun ZhangLing MinQian LiRutie YinPing DingNi LiYi QuDezhi MuJun QinXiaofeng ZhuZhi-Xiong XiaoQintong LiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
spellingShingle |
Science Q Tingjun Lei Peixuan Zhang Xudong Zhang Xue Xiao Jingli Zhang Tong Qiu Qian Dai Yujun Zhang Ling Min Qian Li Rutie Yin Ping Ding Ni Li Yi Qu Dezhi Mu Jun Qin Xiaofeng Zhu Zhi-Xiong Xiao Qintong Li Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation |
description |
Prereplicative complex (pre-RC) formation during G1 is fundamental for cell replication. Here the authors report a role for cyclin K in regulating pre-RC formation in mammalian cells by affecting cyclin E1 activity. |
format |
article |
author |
Tingjun Lei Peixuan Zhang Xudong Zhang Xue Xiao Jingli Zhang Tong Qiu Qian Dai Yujun Zhang Ling Min Qian Li Rutie Yin Ping Ding Ni Li Yi Qu Dezhi Mu Jun Qin Xiaofeng Zhu Zhi-Xiong Xiao Qintong Li |
author_facet |
Tingjun Lei Peixuan Zhang Xudong Zhang Xue Xiao Jingli Zhang Tong Qiu Qian Dai Yujun Zhang Ling Min Qian Li Rutie Yin Ping Ding Ni Li Yi Qu Dezhi Mu Jun Qin Xiaofeng Zhu Zhi-Xiong Xiao Qintong Li |
author_sort |
Tingjun Lei |
title |
Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation |
title_short |
Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation |
title_full |
Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation |
title_fullStr |
Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation |
title_full_unstemmed |
Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation |
title_sort |
cyclin k regulates prereplicative complex assembly to promote mammalian cell proliferation |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/aa0bfdb189444623bd43e33efbfa2ec8 |
work_keys_str_mv |
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