Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation

Prereplicative complex (pre-RC) formation during G1 is fundamental for cell replication. Here the authors report a role for cyclin K in regulating pre-RC formation in mammalian cells by affecting cyclin E1 activity.

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Autores principales: Tingjun Lei, Peixuan Zhang, Xudong Zhang, Xue Xiao, Jingli Zhang, Tong Qiu, Qian Dai, Yujun Zhang, Ling Min, Qian Li, Rutie Yin, Ping Ding, Ni Li, Yi Qu, Dezhi Mu, Jun Qin, Xiaofeng Zhu, Zhi-Xiong Xiao, Qintong Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/aa0bfdb189444623bd43e33efbfa2ec8
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spelling oai:doaj.org-article:aa0bfdb189444623bd43e33efbfa2ec82021-12-02T16:49:23ZCyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation10.1038/s41467-018-04258-w2041-1723https://doaj.org/article/aa0bfdb189444623bd43e33efbfa2ec82018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04258-whttps://doaj.org/toc/2041-1723Prereplicative complex (pre-RC) formation during G1 is fundamental for cell replication. Here the authors report a role for cyclin K in regulating pre-RC formation in mammalian cells by affecting cyclin E1 activity.Tingjun LeiPeixuan ZhangXudong ZhangXue XiaoJingli ZhangTong QiuQian DaiYujun ZhangLing MinQian LiRutie YinPing DingNi LiYi QuDezhi MuJun QinXiaofeng ZhuZhi-Xiong XiaoQintong LiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tingjun Lei
Peixuan Zhang
Xudong Zhang
Xue Xiao
Jingli Zhang
Tong Qiu
Qian Dai
Yujun Zhang
Ling Min
Qian Li
Rutie Yin
Ping Ding
Ni Li
Yi Qu
Dezhi Mu
Jun Qin
Xiaofeng Zhu
Zhi-Xiong Xiao
Qintong Li
Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation
description Prereplicative complex (pre-RC) formation during G1 is fundamental for cell replication. Here the authors report a role for cyclin K in regulating pre-RC formation in mammalian cells by affecting cyclin E1 activity.
format article
author Tingjun Lei
Peixuan Zhang
Xudong Zhang
Xue Xiao
Jingli Zhang
Tong Qiu
Qian Dai
Yujun Zhang
Ling Min
Qian Li
Rutie Yin
Ping Ding
Ni Li
Yi Qu
Dezhi Mu
Jun Qin
Xiaofeng Zhu
Zhi-Xiong Xiao
Qintong Li
author_facet Tingjun Lei
Peixuan Zhang
Xudong Zhang
Xue Xiao
Jingli Zhang
Tong Qiu
Qian Dai
Yujun Zhang
Ling Min
Qian Li
Rutie Yin
Ping Ding
Ni Li
Yi Qu
Dezhi Mu
Jun Qin
Xiaofeng Zhu
Zhi-Xiong Xiao
Qintong Li
author_sort Tingjun Lei
title Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation
title_short Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation
title_full Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation
title_fullStr Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation
title_full_unstemmed Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation
title_sort cyclin k regulates prereplicative complex assembly to promote mammalian cell proliferation
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/aa0bfdb189444623bd43e33efbfa2ec8
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