Dietary thiols accelerate aging of C. elegans

Reactive oxygen species are required for the long lifespan, and glutathione is an antioxidant. Here the authors show that limiting the consumption of dietary thiols, including those naturally derived from the microbiota, increases proteotoxic stress resistance in worms and human cells, and extends C...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ivan Gusarov, Ilya Shamovsky, Bibhusita Pani, Laurent Gautier, Svetlana Eremina, Olga Katkova-Zhukotskaya, Alexander Mironov, Alexander А. Makarov, Evgeny Nudler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aa0cfd08560d47b397240eb792894996
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:aa0cfd08560d47b397240eb792894996
record_format	dspace
spelling	oai:doaj.org-article:aa0cfd08560d47b397240eb7928949962021-12-02T17:01:14ZDietary thiols accelerate aging of C. elegans10.1038/s41467-021-24634-32041-1723https://doaj.org/article/aa0cfd08560d47b397240eb7928949962021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24634-3https://doaj.org/toc/2041-1723Reactive oxygen species are required for the long lifespan, and glutathione is an antioxidant. Here the authors show that limiting the consumption of dietary thiols, including those naturally derived from the microbiota, increases proteotoxic stress resistance in worms and human cells, and extends C. elegans lifespan.Ivan GusarovIlya ShamovskyBibhusita PaniLaurent GautierSvetlana EreminaOlga Katkova-ZhukotskayaAlexander MironovAlexander А. MakarovEvgeny NudlerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ivan Gusarov Ilya Shamovsky Bibhusita Pani Laurent Gautier Svetlana Eremina Olga Katkova-Zhukotskaya Alexander Mironov Alexander А. Makarov Evgeny Nudler Dietary thiols accelerate aging of C. elegans
description	Reactive oxygen species are required for the long lifespan, and glutathione is an antioxidant. Here the authors show that limiting the consumption of dietary thiols, including those naturally derived from the microbiota, increases proteotoxic stress resistance in worms and human cells, and extends C. elegans lifespan.
format	article
author	Ivan Gusarov Ilya Shamovsky Bibhusita Pani Laurent Gautier Svetlana Eremina Olga Katkova-Zhukotskaya Alexander Mironov Alexander А. Makarov Evgeny Nudler
author_facet	Ivan Gusarov Ilya Shamovsky Bibhusita Pani Laurent Gautier Svetlana Eremina Olga Katkova-Zhukotskaya Alexander Mironov Alexander А. Makarov Evgeny Nudler
author_sort	Ivan Gusarov
title	Dietary thiols accelerate aging of C. elegans
title_short	Dietary thiols accelerate aging of C. elegans
title_full	Dietary thiols accelerate aging of C. elegans
title_fullStr	Dietary thiols accelerate aging of C. elegans
title_full_unstemmed	Dietary thiols accelerate aging of C. elegans
title_sort	dietary thiols accelerate aging of c. elegans
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/aa0cfd08560d47b397240eb792894996
work_keys_str_mv	AT ivangusarov dietarythiolsaccelerateagingofcelegans AT ilyashamovsky dietarythiolsaccelerateagingofcelegans AT bibhusitapani dietarythiolsaccelerateagingofcelegans AT laurentgautier dietarythiolsaccelerateagingofcelegans AT svetlanaeremina dietarythiolsaccelerateagingofcelegans AT olgakatkovazhukotskaya dietarythiolsaccelerateagingofcelegans AT alexandermironov dietarythiolsaccelerateagingofcelegans AT alexanderamakarov dietarythiolsaccelerateagingofcelegans AT evgenynudler dietarythiolsaccelerateagingofcelegans
_version_	1718382230087139328

Dietary thiols accelerate aging of C. elegans

Ejemplares similares