Similarities and differences in patterns of germline mutation between mice and humans
Estimates of mutation rates differ between species. Here, Lindsay et al. perform side-by-side analyses of germline mutation rates using multi-sibling mouse and human pedigrees and find different mutation rates between species, also stratified by sex and temporal stage of mutation acquisition.
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Autores principales: | Sarah J. Lindsay, Raheleh Rahbari, Joanna Kaplanis, Thomas Keane, Matthew E. Hurles |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/aa0dc48964e54ac386e118a6c152dd33 |
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