Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

The majority of treatment options for cancers are ineffective due to limited therapeutic targeting. Here, the authors develop bispecific antibodies that effectively target nanomaterials to triple-negative breast cancer cell receptors and deliver therapeutics leading to inhibition of tumour growth.

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Autores principales:	Yu-Cheng Su, Pierre-Alain Burnouf, Kuo-Hsiang Chuang, Bing-Mae Chen, Tian-Lu Cheng, Steve R. Roffler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aa11269ebeb14aaca28beb8fce230033
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spelling	oai:doaj.org-article:aa11269ebeb14aaca28beb8fce2300332021-12-02T17:01:23ZConditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy10.1038/ncomms155072041-1723https://doaj.org/article/aa11269ebeb14aaca28beb8fce2300332017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15507https://doaj.org/toc/2041-1723The majority of treatment options for cancers are ineffective due to limited therapeutic targeting. Here, the authors develop bispecific antibodies that effectively target nanomaterials to triple-negative breast cancer cell receptors and deliver therapeutics leading to inhibition of tumour growth.Yu-Cheng SuPierre-Alain BurnoufKuo-Hsiang ChuangBing-Mae ChenTian-Lu ChengSteve R. RofflerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yu-Cheng Su Pierre-Alain Burnouf Kuo-Hsiang Chuang Bing-Mae Chen Tian-Lu Cheng Steve R. Roffler Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy
description	The majority of treatment options for cancers are ineffective due to limited therapeutic targeting. Here, the authors develop bispecific antibodies that effectively target nanomaterials to triple-negative breast cancer cell receptors and deliver therapeutics leading to inhibition of tumour growth.
format	article
author	Yu-Cheng Su Pierre-Alain Burnouf Kuo-Hsiang Chuang Bing-Mae Chen Tian-Lu Cheng Steve R. Roffler
author_facet	Yu-Cheng Su Pierre-Alain Burnouf Kuo-Hsiang Chuang Bing-Mae Chen Tian-Lu Cheng Steve R. Roffler
author_sort	Yu-Cheng Su
title	Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy
title_short	Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy
title_full	Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy
title_fullStr	Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy
title_full_unstemmed	Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy
title_sort	conditional internalization of pegylated nanomedicines by peg engagers for triple negative breast cancer therapy
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/aa11269ebeb14aaca28beb8fce230033
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Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

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