High-dimensional genomic data bias correction and data integration using MANCIE

Analyses of data from high-throughput genomic technologies are challenging given large data dimensionality. Here, Liu and colleagues describe a method called MANCIE (Matrix Analysis and Normalization by Concordant Information Enhancement) that can conduct genomic data normalization and bias correcti...

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Autores principales: Chongzhi Zang, Tao Wang, Ke Deng, Bo Li, Sheng’en Hu, Qian Qin, Tengfei Xiao, Shihua Zhang, Clifford A. Meyer, Housheng Hansen He, Myles Brown, Jun S. Liu, Yang Xie, X. Shirley Liu
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/aa14d67d31a54ea9b4ff50393da16654
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spelling oai:doaj.org-article:aa14d67d31a54ea9b4ff50393da166542021-12-02T17:31:51ZHigh-dimensional genomic data bias correction and data integration using MANCIE10.1038/ncomms113052041-1723https://doaj.org/article/aa14d67d31a54ea9b4ff50393da166542016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11305https://doaj.org/toc/2041-1723Analyses of data from high-throughput genomic technologies are challenging given large data dimensionality. Here, Liu and colleagues describe a method called MANCIE (Matrix Analysis and Normalization by Concordant Information Enhancement) that can conduct genomic data normalization and bias correction to detect biologically relevant information.Chongzhi ZangTao WangKe DengBo LiSheng’en HuQian QinTengfei XiaoShihua ZhangClifford A. MeyerHousheng Hansen HeMyles BrownJun S. LiuYang XieX. Shirley LiuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chongzhi Zang
Tao Wang
Ke Deng
Bo Li
Sheng’en Hu
Qian Qin
Tengfei Xiao
Shihua Zhang
Clifford A. Meyer
Housheng Hansen He
Myles Brown
Jun S. Liu
Yang Xie
X. Shirley Liu
High-dimensional genomic data bias correction and data integration using MANCIE
description Analyses of data from high-throughput genomic technologies are challenging given large data dimensionality. Here, Liu and colleagues describe a method called MANCIE (Matrix Analysis and Normalization by Concordant Information Enhancement) that can conduct genomic data normalization and bias correction to detect biologically relevant information.
format article
author Chongzhi Zang
Tao Wang
Ke Deng
Bo Li
Sheng’en Hu
Qian Qin
Tengfei Xiao
Shihua Zhang
Clifford A. Meyer
Housheng Hansen He
Myles Brown
Jun S. Liu
Yang Xie
X. Shirley Liu
author_facet Chongzhi Zang
Tao Wang
Ke Deng
Bo Li
Sheng’en Hu
Qian Qin
Tengfei Xiao
Shihua Zhang
Clifford A. Meyer
Housheng Hansen He
Myles Brown
Jun S. Liu
Yang Xie
X. Shirley Liu
author_sort Chongzhi Zang
title High-dimensional genomic data bias correction and data integration using MANCIE
title_short High-dimensional genomic data bias correction and data integration using MANCIE
title_full High-dimensional genomic data bias correction and data integration using MANCIE
title_fullStr High-dimensional genomic data bias correction and data integration using MANCIE
title_full_unstemmed High-dimensional genomic data bias correction and data integration using MANCIE
title_sort high-dimensional genomic data bias correction and data integration using mancie
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/aa14d67d31a54ea9b4ff50393da16654
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