High-dimensional genomic data bias correction and data integration using MANCIE
Analyses of data from high-throughput genomic technologies are challenging given large data dimensionality. Here, Liu and colleagues describe a method called MANCIE (Matrix Analysis and Normalization by Concordant Information Enhancement) that can conduct genomic data normalization and bias correcti...
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Nature Portfolio
2016
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oai:doaj.org-article:aa14d67d31a54ea9b4ff50393da166542021-12-02T17:31:51ZHigh-dimensional genomic data bias correction and data integration using MANCIE10.1038/ncomms113052041-1723https://doaj.org/article/aa14d67d31a54ea9b4ff50393da166542016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11305https://doaj.org/toc/2041-1723Analyses of data from high-throughput genomic technologies are challenging given large data dimensionality. Here, Liu and colleagues describe a method called MANCIE (Matrix Analysis and Normalization by Concordant Information Enhancement) that can conduct genomic data normalization and bias correction to detect biologically relevant information.Chongzhi ZangTao WangKe DengBo LiSheng’en HuQian QinTengfei XiaoShihua ZhangClifford A. MeyerHousheng Hansen HeMyles BrownJun S. LiuYang XieX. Shirley LiuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016) |
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Science Q Chongzhi Zang Tao Wang Ke Deng Bo Li Sheng’en Hu Qian Qin Tengfei Xiao Shihua Zhang Clifford A. Meyer Housheng Hansen He Myles Brown Jun S. Liu Yang Xie X. Shirley Liu High-dimensional genomic data bias correction and data integration using MANCIE |
description |
Analyses of data from high-throughput genomic technologies are challenging given large data dimensionality. Here, Liu and colleagues describe a method called MANCIE (Matrix Analysis and Normalization by Concordant Information Enhancement) that can conduct genomic data normalization and bias correction to detect biologically relevant information. |
format |
article |
author |
Chongzhi Zang Tao Wang Ke Deng Bo Li Sheng’en Hu Qian Qin Tengfei Xiao Shihua Zhang Clifford A. Meyer Housheng Hansen He Myles Brown Jun S. Liu Yang Xie X. Shirley Liu |
author_facet |
Chongzhi Zang Tao Wang Ke Deng Bo Li Sheng’en Hu Qian Qin Tengfei Xiao Shihua Zhang Clifford A. Meyer Housheng Hansen He Myles Brown Jun S. Liu Yang Xie X. Shirley Liu |
author_sort |
Chongzhi Zang |
title |
High-dimensional genomic data bias correction and data integration using MANCIE |
title_short |
High-dimensional genomic data bias correction and data integration using MANCIE |
title_full |
High-dimensional genomic data bias correction and data integration using MANCIE |
title_fullStr |
High-dimensional genomic data bias correction and data integration using MANCIE |
title_full_unstemmed |
High-dimensional genomic data bias correction and data integration using MANCIE |
title_sort |
high-dimensional genomic data bias correction and data integration using mancie |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/aa14d67d31a54ea9b4ff50393da16654 |
work_keys_str_mv |
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