Application of rapid artificial cardiac pacing in thoracic endovascular aortic repair in aged patients

Jun Chen,1,* Wenhui Huang,2,* Songyuan Luo,2,* Dahao Yang,1 Zhengrong Xu,1 Jianfang Luo21Department of Angiocardiopathy, Affiliated Baoan Hospital of Southern Medical University, Shenzhen City, People's Republic of China; 2Department of Cardiology, Guangdong Cardiovascular Institute, Guangdo...

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Autores principales: Chen J, Huang WH, Luo SY, Yang DH, Xu ZR, Luo JF
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Publicado: Dove Medical Press 2013
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spelling oai:doaj.org-article:aa1720d1685e429a8f3369e4cfba01962021-12-02T00:33:34ZApplication of rapid artificial cardiac pacing in thoracic endovascular aortic repair in aged patients1178-1998https://doaj.org/article/aa1720d1685e429a8f3369e4cfba01962013-12-01T00:00:00Zhttps://www.dovepress.com/application-of-rapid-artificial-cardiac-pacing-in-thoracic-endovascula-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Jun Chen,1,* Wenhui Huang,2,* Songyuan Luo,2,* Dahao Yang,1 Zhengrong Xu,1 Jianfang Luo21Department of Angiocardiopathy, Affiliated Baoan Hospital of Southern Medical University, Shenzhen City, People's Republic of China; 2Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, People's Republic of China*These authors contributed equally to this workObjective: To compare the safety, efficacy, and impact on stent graft positioning between rapid artificial cardiac pacing (RACP), induced hypotension and sodium nitroprusside (SNP) induced hypotension during thoracic endovascular aortic repair (TEVAR) for Stanford B aortic dissection.Methods: One hundred and sixty-eight patients, who were diagnosed with Stanford B aortic dissection and who underwent selective TEVAR in Guangdong General Hospital and the People's Hospital of Baoan District, Shenzhen, People's Republic of China, were enrolled in this study. Patients were randomly divided into a RACP group (n=77) and a SNP group (n=91). During localization and deployment of the stent graft, hypotension was induced by RACP or intravenous SNP, according to randomization. Hemodynamics, landing precision (deviation from planned placement site), duration of procedure, renal function, neurocognitive function, and incidence of endoleaks and paraplegia/hemiplegia were compared. Except for methods of inducing hypotension, TEVAR was performed according to the same protocol in each group.Results: RACP was successfully performed in all patients assigned to the RACP group. Compared with the SNP group, blood pressure was significantly lower (43±5 versus 81±6 mmHg, P=0.003) and the restoration time of blood pressure and the operation duration were significantly shorter (7±2 versus 451±87 seconds, P<0.001; 87±15 versus 106±18 minutes, P<0.001, respectively) in the RACP group. Stent graft localization/deployment was more precise in the RACP group (2±1 versus 5±2 mm, P<0.001). Compared to baseline, there was no significant change after TEVAR in either group in regard to renal function, neurocognitive function, and incidence of endoleaks and paraplegia/hemiplegia.Conclusion: RACP can be safely applied to patients undergoing TEVAR for Stanford B dissection. RACP can shorten the operation duration and facilitate precise graft localization/deployment.Keywords: Stanford B aortic dissection, endovascular repair, rapid artificial cardiac pacing, precise graft deploymentChen JHuang WHLuo SYYang DHXu ZRLuo JFDove Medical PressarticleStanford B aortic dissectionendovascular repairrapid right ventricular pacingprecise graft deploymentGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 9, Pp 73-78 (2013)
institution DOAJ
collection DOAJ
language EN
topic Stanford B aortic dissection
endovascular repair
rapid right ventricular pacing
precise graft deployment
Geriatrics
RC952-954.6
spellingShingle Stanford B aortic dissection
endovascular repair
rapid right ventricular pacing
precise graft deployment
Geriatrics
RC952-954.6
Chen J
Huang WH
Luo SY
Yang DH
Xu ZR
Luo JF
Application of rapid artificial cardiac pacing in thoracic endovascular aortic repair in aged patients
description Jun Chen,1,* Wenhui Huang,2,* Songyuan Luo,2,* Dahao Yang,1 Zhengrong Xu,1 Jianfang Luo21Department of Angiocardiopathy, Affiliated Baoan Hospital of Southern Medical University, Shenzhen City, People's Republic of China; 2Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, People's Republic of China*These authors contributed equally to this workObjective: To compare the safety, efficacy, and impact on stent graft positioning between rapid artificial cardiac pacing (RACP), induced hypotension and sodium nitroprusside (SNP) induced hypotension during thoracic endovascular aortic repair (TEVAR) for Stanford B aortic dissection.Methods: One hundred and sixty-eight patients, who were diagnosed with Stanford B aortic dissection and who underwent selective TEVAR in Guangdong General Hospital and the People's Hospital of Baoan District, Shenzhen, People's Republic of China, were enrolled in this study. Patients were randomly divided into a RACP group (n=77) and a SNP group (n=91). During localization and deployment of the stent graft, hypotension was induced by RACP or intravenous SNP, according to randomization. Hemodynamics, landing precision (deviation from planned placement site), duration of procedure, renal function, neurocognitive function, and incidence of endoleaks and paraplegia/hemiplegia were compared. Except for methods of inducing hypotension, TEVAR was performed according to the same protocol in each group.Results: RACP was successfully performed in all patients assigned to the RACP group. Compared with the SNP group, blood pressure was significantly lower (43±5 versus 81±6 mmHg, P=0.003) and the restoration time of blood pressure and the operation duration were significantly shorter (7±2 versus 451±87 seconds, P<0.001; 87±15 versus 106±18 minutes, P<0.001, respectively) in the RACP group. Stent graft localization/deployment was more precise in the RACP group (2±1 versus 5±2 mm, P<0.001). Compared to baseline, there was no significant change after TEVAR in either group in regard to renal function, neurocognitive function, and incidence of endoleaks and paraplegia/hemiplegia.Conclusion: RACP can be safely applied to patients undergoing TEVAR for Stanford B dissection. RACP can shorten the operation duration and facilitate precise graft localization/deployment.Keywords: Stanford B aortic dissection, endovascular repair, rapid artificial cardiac pacing, precise graft deployment
format article
author Chen J
Huang WH
Luo SY
Yang DH
Xu ZR
Luo JF
author_facet Chen J
Huang WH
Luo SY
Yang DH
Xu ZR
Luo JF
author_sort Chen J
title Application of rapid artificial cardiac pacing in thoracic endovascular aortic repair in aged patients
title_short Application of rapid artificial cardiac pacing in thoracic endovascular aortic repair in aged patients
title_full Application of rapid artificial cardiac pacing in thoracic endovascular aortic repair in aged patients
title_fullStr Application of rapid artificial cardiac pacing in thoracic endovascular aortic repair in aged patients
title_full_unstemmed Application of rapid artificial cardiac pacing in thoracic endovascular aortic repair in aged patients
title_sort application of rapid artificial cardiac pacing in thoracic endovascular aortic repair in aged patients
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/aa1720d1685e429a8f3369e4cfba0196
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