The Global Burden of Disease Study Estimates of Brazil’s Cervical Cancer Burden

Background: Cervical cancer represents an important preventable cause of morbidity and mortality in developing countries such as Brazil. Investigating temporal evolution of a disease burden in the different realities of the country is essential for improving public policies. Objective: To describe t...

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Autores principales:	Nathalia V. S. Reis, Brenda B. Andrade, Maximiliano R. Guerra, Maria Tereza B. Teixeira, Deborah C. Malta, Valéria M. A. Passos
Formato:	article
Lenguaje:	EN
Publicado:	Ubiquity Press 2020
Materias:	Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/aa1b29dae4ec49f6a2109d6817b6fe18
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spelling	oai:doaj.org-article:aa1b29dae4ec49f6a2109d6817b6fe182021-12-02T12:26:33ZThe Global Burden of Disease Study Estimates of Brazil’s Cervical Cancer Burden2214-999610.5334/aogh.2756https://doaj.org/article/aa1b29dae4ec49f6a2109d6817b6fe182020-06-01T00:00:00Zhttps://annalsofglobalhealth.org/articles/2756https://doaj.org/toc/2214-9996Background: Cervical cancer represents an important preventable cause of morbidity and mortality in developing countries such as Brazil. Investigating temporal evolution of a disease burden in the different realities of the country is essential for improving public policies. Objective: To describe the national and subnational burden of cervical cancer, based on the estimates of the 2017 Global Burden of Disease study. Methods: Descriptive study of premature mortality (years of life lost [YLL]) and burden of disease (disability-adjusted life years [DALYs]) associated with cervical cancer among Brazilian women aged 25–64 years, between 2000 and 2017. Findings: During the study period, age-standardized incidence decreased from 23.53 (22.79–24.26) to 18.39 (17.63–19.17) per 100,000 women, while mortality rates decreased from 11.3 (11.05–11.56) to 7.74 (7.49–8.02) per 100,000 women. These rates were about two to three times greater than equivalent rates in a developed country, such as England: 11.98 (11.45–12.55) to 10.37 (9.85–10.9), and 3.75 (3.68–3.84) to 2.82 (2.75–2.9) per 100,000 women, respectively. Poorer regions of Brazil had greater rates of the disease; for instance, Amapá State in the Northern Region had rates twice as high as the national rates during the same period. Cervical cancer was the leading cause of premature cancer-related mortality (YLL = 100.69, 91.48–110.61 per 100,000 women) among young women (25–29 years) in Brazil and eight federation units of all country regions except the Southeast in 2017. There was a decrease in the burden of cervical cancer in Brazil from 339.59 (330.82–348.83) DALYs per 100,000 women in 2000 to 238.99 (230.45–247.99) DALYs per 100,000 women in 2017. Conclusion: Although there has been a reduction in the burden of cervical cancer in Brazil, the rates remain high, mainly among young women. The persistence of inequalities between regions of Brazil suggests the importance of socioeconomic determinants in the burden for this cancer.Nathalia V. S. ReisBrenda B. AndradeMaximiliano R. GuerraMaria Tereza B. TeixeiraDeborah C. MaltaValéria M. A. PassosUbiquity PressarticleInfectious and parasitic diseasesRC109-216Public aspects of medicineRA1-1270ENAnnals of Global Health, Vol 86, Iss 1 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
spellingShingle	Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270 Nathalia V. S. Reis Brenda B. Andrade Maximiliano R. Guerra Maria Tereza B. Teixeira Deborah C. Malta Valéria M. A. Passos The Global Burden of Disease Study Estimates of Brazil’s Cervical Cancer Burden
description	Background: Cervical cancer represents an important preventable cause of morbidity and mortality in developing countries such as Brazil. Investigating temporal evolution of a disease burden in the different realities of the country is essential for improving public policies. Objective: To describe the national and subnational burden of cervical cancer, based on the estimates of the 2017 Global Burden of Disease study. Methods: Descriptive study of premature mortality (years of life lost [YLL]) and burden of disease (disability-adjusted life years [DALYs]) associated with cervical cancer among Brazilian women aged 25–64 years, between 2000 and 2017. Findings: During the study period, age-standardized incidence decreased from 23.53 (22.79–24.26) to 18.39 (17.63–19.17) per 100,000 women, while mortality rates decreased from 11.3 (11.05–11.56) to 7.74 (7.49–8.02) per 100,000 women. These rates were about two to three times greater than equivalent rates in a developed country, such as England: 11.98 (11.45–12.55) to 10.37 (9.85–10.9), and 3.75 (3.68–3.84) to 2.82 (2.75–2.9) per 100,000 women, respectively. Poorer regions of Brazil had greater rates of the disease; for instance, Amapá State in the Northern Region had rates twice as high as the national rates during the same period. Cervical cancer was the leading cause of premature cancer-related mortality (YLL = 100.69, 91.48–110.61 per 100,000 women) among young women (25–29 years) in Brazil and eight federation units of all country regions except the Southeast in 2017. There was a decrease in the burden of cervical cancer in Brazil from 339.59 (330.82–348.83) DALYs per 100,000 women in 2000 to 238.99 (230.45–247.99) DALYs per 100,000 women in 2017. Conclusion: Although there has been a reduction in the burden of cervical cancer in Brazil, the rates remain high, mainly among young women. The persistence of inequalities between regions of Brazil suggests the importance of socioeconomic determinants in the burden for this cancer.
format	article
author	Nathalia V. S. Reis Brenda B. Andrade Maximiliano R. Guerra Maria Tereza B. Teixeira Deborah C. Malta Valéria M. A. Passos
author_facet	Nathalia V. S. Reis Brenda B. Andrade Maximiliano R. Guerra Maria Tereza B. Teixeira Deborah C. Malta Valéria M. A. Passos
author_sort	Nathalia V. S. Reis
title	The Global Burden of Disease Study Estimates of Brazil’s Cervical Cancer Burden
title_short	The Global Burden of Disease Study Estimates of Brazil’s Cervical Cancer Burden
title_full	The Global Burden of Disease Study Estimates of Brazil’s Cervical Cancer Burden
title_fullStr	The Global Burden of Disease Study Estimates of Brazil’s Cervical Cancer Burden
title_full_unstemmed	The Global Burden of Disease Study Estimates of Brazil’s Cervical Cancer Burden
title_sort	global burden of disease study estimates of brazil’s cervical cancer burden
publisher	Ubiquity Press
publishDate	2020
url	https://doaj.org/article/aa1b29dae4ec49f6a2109d6817b6fe18
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The Global Burden of Disease Study Estimates of Brazil’s Cervical Cancer Burden

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