High TB burden and low notification rates in the Philippines: The 2016 national TB prevalence survey.

<h4>Setting</h4>The 3rd national tuberculosis (TB) survey in the Philippines in 2007 reported a significant decline in the prevalence of TB. Since then, more significant investments for TB control have been made, yet TB burden estimates from routine surveillance data remain relatively st...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mary Ann D Lansang, Marissa M Alejandria, Irwin Law, Noel R Juban, Maria Lourdes E Amarillo, Olivia T Sison, Jose Rene B Cruz, Concepcion F Ang, Joseph Adrian L Buensalido, Johanna Patricia A Cañal, Nina T Castillo-Carandang, Cynthia P Cordero, Donna Mae G Gaviola, Mary Ann J Ladia, Jacinto Blas V Mantaring, Myrna T Mendoza, Maria Sonia S Salamat, Hilton Y Lam, Marina Tadolini, Anna Marie Celina G Garfin, Philippine NTPS 2016 Group
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/aa206b87b30e435789890e057498d23a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:aa206b87b30e435789890e057498d23a
record_format	dspace
spelling	oai:doaj.org-article:aa206b87b30e435789890e057498d23a2021-11-25T06:23:35ZHigh TB burden and low notification rates in the Philippines: The 2016 national TB prevalence survey.1932-620310.1371/journal.pone.0252240https://doaj.org/article/aa206b87b30e435789890e057498d23a2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0252240https://doaj.org/toc/1932-6203<h4>Setting</h4>The 3rd national tuberculosis (TB) survey in the Philippines in 2007 reported a significant decline in the prevalence of TB. Since then, more significant investments for TB control have been made, yet TB burden estimates from routine surveillance data remain relatively stable.<h4>Objective</h4>To estimate the prevalence of bacteriologically confirmed pulmonary TB in the Philippines amongst individuals aged ≥15 years in 2016.<h4>Design</h4>In March-December 2016, we conducted a population-based survey with stratified, multi-stage cluster sampling of residents in 106 clusters aged ≥15 years. Survey participants were screened for TB by symptom-based interview and digital chest X-ray. Those with cough ≥2 weeks and/or haemoptysis and/or chest X-ray suggestive of TB were requested to submit 2 sputum specimens for Xpert MTB/RIF, direct sputum smear microscopy using LED fluorescent microscopy, and mycobacterial solid culture (Ogawa method). Bacteriologically confirmed pulmonary TB was defined as MTB culture positive and/or Xpert positive.<h4>Results</h4>There were 46,689 individuals interviewed, and 41,444 (88.8%) consented to a chest X-ray. There were 18,597 (39.8%) eligible for sputum examination and 16,242 (87.3%) submitted at least one specimen. Out of 16,058 sputum-eligible participants, 183 (1.1%) were smear-positive. There were 466 bacteriologically confirmed TB cases: 238 (51.1%) Xpert positive, 69 (14.8%) culture positive, and 159 (34.1%) positive by both Xpert and culture. The estimated TB prevalence per 100,000 population aged ≥15 years was 434 (95% CI: 350-518) for smear-positive TB, and 1,159 (95% CI: 1,016-1,301) for bacteriologically confirmed TB.<h4>Conclusion</h4>This nationally representative survey found that the TB burden in the Philippines in 2016 was higher than estimated from routine TB surveillance data. There was no evidence of a decline in smear and culture positive TB from the 2007 survey despite significant investments in TB control. New strategies for case-finding and patient-centered care must be intensified and expanded.Mary Ann D LansangMarissa M AlejandriaIrwin LawNoel R JubanMaria Lourdes E AmarilloOlivia T SisonJose Rene B CruzConcepcion F AngJoseph Adrian L BuensalidoJohanna Patricia A CañalNina T Castillo-CarandangCynthia P CorderoDonna Mae G GaviolaMary Ann J LadiaJacinto Blas V MantaringMyrna T MendozaMaria Sonia S SalamatHilton Y LamMarina TadoliniAnna Marie Celina G GarfinPhilippine NTPS 2016 GroupPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0252240 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mary Ann D Lansang Marissa M Alejandria Irwin Law Noel R Juban Maria Lourdes E Amarillo Olivia T Sison Jose Rene B Cruz Concepcion F Ang Joseph Adrian L Buensalido Johanna Patricia A Cañal Nina T Castillo-Carandang Cynthia P Cordero Donna Mae G Gaviola Mary Ann J Ladia Jacinto Blas V Mantaring Myrna T Mendoza Maria Sonia S Salamat Hilton Y Lam Marina Tadolini Anna Marie Celina G Garfin Philippine NTPS 2016 Group High TB burden and low notification rates in the Philippines: The 2016 national TB prevalence survey.
description	<h4>Setting</h4>The 3rd national tuberculosis (TB) survey in the Philippines in 2007 reported a significant decline in the prevalence of TB. Since then, more significant investments for TB control have been made, yet TB burden estimates from routine surveillance data remain relatively stable.<h4>Objective</h4>To estimate the prevalence of bacteriologically confirmed pulmonary TB in the Philippines amongst individuals aged ≥15 years in 2016.<h4>Design</h4>In March-December 2016, we conducted a population-based survey with stratified, multi-stage cluster sampling of residents in 106 clusters aged ≥15 years. Survey participants were screened for TB by symptom-based interview and digital chest X-ray. Those with cough ≥2 weeks and/or haemoptysis and/or chest X-ray suggestive of TB were requested to submit 2 sputum specimens for Xpert MTB/RIF, direct sputum smear microscopy using LED fluorescent microscopy, and mycobacterial solid culture (Ogawa method). Bacteriologically confirmed pulmonary TB was defined as MTB culture positive and/or Xpert positive.<h4>Results</h4>There were 46,689 individuals interviewed, and 41,444 (88.8%) consented to a chest X-ray. There were 18,597 (39.8%) eligible for sputum examination and 16,242 (87.3%) submitted at least one specimen. Out of 16,058 sputum-eligible participants, 183 (1.1%) were smear-positive. There were 466 bacteriologically confirmed TB cases: 238 (51.1%) Xpert positive, 69 (14.8%) culture positive, and 159 (34.1%) positive by both Xpert and culture. The estimated TB prevalence per 100,000 population aged ≥15 years was 434 (95% CI: 350-518) for smear-positive TB, and 1,159 (95% CI: 1,016-1,301) for bacteriologically confirmed TB.<h4>Conclusion</h4>This nationally representative survey found that the TB burden in the Philippines in 2016 was higher than estimated from routine TB surveillance data. There was no evidence of a decline in smear and culture positive TB from the 2007 survey despite significant investments in TB control. New strategies for case-finding and patient-centered care must be intensified and expanded.
format	article
author	Mary Ann D Lansang Marissa M Alejandria Irwin Law Noel R Juban Maria Lourdes E Amarillo Olivia T Sison Jose Rene B Cruz Concepcion F Ang Joseph Adrian L Buensalido Johanna Patricia A Cañal Nina T Castillo-Carandang Cynthia P Cordero Donna Mae G Gaviola Mary Ann J Ladia Jacinto Blas V Mantaring Myrna T Mendoza Maria Sonia S Salamat Hilton Y Lam Marina Tadolini Anna Marie Celina G Garfin Philippine NTPS 2016 Group
author_facet	Mary Ann D Lansang Marissa M Alejandria Irwin Law Noel R Juban Maria Lourdes E Amarillo Olivia T Sison Jose Rene B Cruz Concepcion F Ang Joseph Adrian L Buensalido Johanna Patricia A Cañal Nina T Castillo-Carandang Cynthia P Cordero Donna Mae G Gaviola Mary Ann J Ladia Jacinto Blas V Mantaring Myrna T Mendoza Maria Sonia S Salamat Hilton Y Lam Marina Tadolini Anna Marie Celina G Garfin Philippine NTPS 2016 Group
author_sort	Mary Ann D Lansang
title	High TB burden and low notification rates in the Philippines: The 2016 national TB prevalence survey.
title_short	High TB burden and low notification rates in the Philippines: The 2016 national TB prevalence survey.
title_full	High TB burden and low notification rates in the Philippines: The 2016 national TB prevalence survey.
title_fullStr	High TB burden and low notification rates in the Philippines: The 2016 national TB prevalence survey.
title_full_unstemmed	High TB burden and low notification rates in the Philippines: The 2016 national TB prevalence survey.
title_sort	high tb burden and low notification rates in the philippines: the 2016 national tb prevalence survey.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/aa206b87b30e435789890e057498d23a
work_keys_str_mv	AT maryanndlansang hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT marissamalejandria hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT irwinlaw hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT noelrjuban hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT marialourdeseamarillo hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT oliviatsison hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT joserenebcruz hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT concepcionfang hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT josephadrianlbuensalido hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT johannapatriciaacanal hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT ninatcastillocarandang hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT cynthiapcordero hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT donnamaeggaviola hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT maryannjladia hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT jacintoblasvmantaring hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT myrnatmendoza hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT mariasoniassalamat hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT hiltonylam hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT marinatadolini hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT annamariecelinaggarfin hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey AT philippinentps2016group hightbburdenandlownotificationratesinthephilippinesthe2016nationaltbprevalencesurvey
_version_	1718413819984740352

High TB burden and low notification rates in the Philippines: The 2016 national TB prevalence survey.

Ejemplares similares