Myosin 7 and its adaptors link cadherins to actin

Cadherin is essential for mechanotransduction and myosin-adaptor-harmonin complexes anchor it to actin. Here the authors present the structures of myosin 7 MF2 domains bound to the harmonin PDZ3c domain and give insights into myosin-adaptor-harmonin complex assembly.

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Autores principales:	I-Mei Yu, Vicente J. Planelles-Herrero, Yannick Sourigues, Dihia Moussaoui, Helena Sirkia, Carlos Kikuti, David Stroebel, Margaret A. Titus, Anne Houdusse
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aa24a24d03664dbc891f02ce9745c6cd
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spelling	oai:doaj.org-article:aa24a24d03664dbc891f02ce9745c6cd2021-12-02T17:06:26ZMyosin 7 and its adaptors link cadherins to actin10.1038/ncomms158642041-1723https://doaj.org/article/aa24a24d03664dbc891f02ce9745c6cd2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15864https://doaj.org/toc/2041-1723Cadherin is essential for mechanotransduction and myosin-adaptor-harmonin complexes anchor it to actin. Here the authors present the structures of myosin 7 MF2 domains bound to the harmonin PDZ3c domain and give insights into myosin-adaptor-harmonin complex assembly.I-Mei YuVicente J. Planelles-HerreroYannick SouriguesDihia MoussaouiHelena SirkiaCarlos KikutiDavid StroebelMargaret A. TitusAnne HoudusseNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q I-Mei Yu Vicente J. Planelles-Herrero Yannick Sourigues Dihia Moussaoui Helena Sirkia Carlos Kikuti David Stroebel Margaret A. Titus Anne Houdusse Myosin 7 and its adaptors link cadherins to actin
description	Cadherin is essential for mechanotransduction and myosin-adaptor-harmonin complexes anchor it to actin. Here the authors present the structures of myosin 7 MF2 domains bound to the harmonin PDZ3c domain and give insights into myosin-adaptor-harmonin complex assembly.
format	article
author	I-Mei Yu Vicente J. Planelles-Herrero Yannick Sourigues Dihia Moussaoui Helena Sirkia Carlos Kikuti David Stroebel Margaret A. Titus Anne Houdusse
author_facet	I-Mei Yu Vicente J. Planelles-Herrero Yannick Sourigues Dihia Moussaoui Helena Sirkia Carlos Kikuti David Stroebel Margaret A. Titus Anne Houdusse
author_sort	I-Mei Yu
title	Myosin 7 and its adaptors link cadherins to actin
title_short	Myosin 7 and its adaptors link cadherins to actin
title_full	Myosin 7 and its adaptors link cadherins to actin
title_fullStr	Myosin 7 and its adaptors link cadherins to actin
title_full_unstemmed	Myosin 7 and its adaptors link cadherins to actin
title_sort	myosin 7 and its adaptors link cadherins to actin
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/aa24a24d03664dbc891f02ce9745c6cd
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Myosin 7 and its adaptors link cadherins to actin

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