Selective pharmacological targeting of a DEAD box RNA helicase.

Selective pharmacological targeting of a DEAD box RNA helicase.

RNA helicases represent a large family of proteins implicated in many biological processes including ribosome biogenesis, splicing, translation and mRNA degradation. However, these proteins have little substrate specificity, making inhibition of selected helicases a challenging problem. The prototyp...

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Bibliographic Details
Main Authors: Lisa Lindqvist, Monika Oberer, Mikhail Reibarkh, Regina Cencic, Marie-Eve Bordeleau, Emily Vogt, Assen Marintchev, Junichi Tanaka, Francois Fagotto, Michael Altmann, Gerhard Wagner, Jerry Pelletier
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2008
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/aa2686c7919142e588b948d711ed23c7
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https://doaj.org/article/aa2686c7919142e588b948d711ed23c7

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