Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis

Lineage segregation from conception to gastrulation has been mapped at the single cell level in mouse, human and monkey. Here, the authors provide a comprehensive analysis of porcine preimplantation development using single cell RNA-seq; mapping metabolic changes, X chromosome inactivation and signa...

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Autores principales: Priscila Ramos-Ibeas, Fei Sang, Qifan Zhu, Walfred W. C. Tang, Sarah Withey, Doris Klisch, Liam Wood, Matt Loose, M. Azim Surani, Ramiro Alberio
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/aa29d00c859347f6bccca210653ecca1
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spelling oai:doaj.org-article:aa29d00c859347f6bccca210653ecca12021-12-02T17:32:24ZPluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis10.1038/s41467-019-08387-82041-1723https://doaj.org/article/aa29d00c859347f6bccca210653ecca12019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08387-8https://doaj.org/toc/2041-1723Lineage segregation from conception to gastrulation has been mapped at the single cell level in mouse, human and monkey. Here, the authors provide a comprehensive analysis of porcine preimplantation development using single cell RNA-seq; mapping metabolic changes, X chromosome inactivation and signalling pathways.Priscila Ramos-IbeasFei SangQifan ZhuWalfred W. C. TangSarah WitheyDoris KlischLiam WoodMatt LooseM. Azim SuraniRamiro AlberioNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Priscila Ramos-Ibeas
Fei Sang
Qifan Zhu
Walfred W. C. Tang
Sarah Withey
Doris Klisch
Liam Wood
Matt Loose
M. Azim Surani
Ramiro Alberio
Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis
description Lineage segregation from conception to gastrulation has been mapped at the single cell level in mouse, human and monkey. Here, the authors provide a comprehensive analysis of porcine preimplantation development using single cell RNA-seq; mapping metabolic changes, X chromosome inactivation and signalling pathways.
format article
author Priscila Ramos-Ibeas
Fei Sang
Qifan Zhu
Walfred W. C. Tang
Sarah Withey
Doris Klisch
Liam Wood
Matt Loose
M. Azim Surani
Ramiro Alberio
author_facet Priscila Ramos-Ibeas
Fei Sang
Qifan Zhu
Walfred W. C. Tang
Sarah Withey
Doris Klisch
Liam Wood
Matt Loose
M. Azim Surani
Ramiro Alberio
author_sort Priscila Ramos-Ibeas
title Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis
title_short Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis
title_full Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis
title_fullStr Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis
title_full_unstemmed Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis
title_sort pluripotency and x chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/aa29d00c859347f6bccca210653ecca1
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