Temporary treatment during primary HIV infection does not affect virologic response to subsequent long-term treatment.

Temporary cART during primary HIV-infection (PHI) did not select for drug resistance mutations after treatment interruption and did not affect the subsequent virological response to long-term cART. Our data demonstrate that fear of drug resistance development is not a valid argument to refrain from...

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Autores principales:	Marlous L Grijsen, Ferdinand W N M Wit, Suzanne Jurriaans, Frank P Kroon, Emile F Schippers, Peter Koopmans, Luuk Gras, Joep M A Lange, Jan M Prins, Primo-SHM Study Group
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/aa29d1b1c52a4b98a97ba1747b59e561
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spelling	oai:doaj.org-article:aa29d1b1c52a4b98a97ba1747b59e5612021-11-18T08:25:10ZTemporary treatment during primary HIV infection does not affect virologic response to subsequent long-term treatment.1932-620310.1371/journal.pone.0089639https://doaj.org/article/aa29d1b1c52a4b98a97ba1747b59e5612014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24699072/?tool=EBIhttps://doaj.org/toc/1932-6203Temporary cART during primary HIV-infection (PHI) did not select for drug resistance mutations after treatment interruption and did not affect the subsequent virological response to long-term cART. Our data demonstrate that fear of drug resistance development is not a valid argument to refrain from temporary early treatment during PHI.Marlous L GrijsenFerdinand W N M WitSuzanne JurriaansFrank P KroonEmile F SchippersPeter KoopmansLuuk GrasJoep M A LangeJan M PrinsPrimo-SHM Study GroupPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 4, p e89639 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Marlous L Grijsen Ferdinand W N M Wit Suzanne Jurriaans Frank P Kroon Emile F Schippers Peter Koopmans Luuk Gras Joep M A Lange Jan M Prins Primo-SHM Study Group Temporary treatment during primary HIV infection does not affect virologic response to subsequent long-term treatment.
description	Temporary cART during primary HIV-infection (PHI) did not select for drug resistance mutations after treatment interruption and did not affect the subsequent virological response to long-term cART. Our data demonstrate that fear of drug resistance development is not a valid argument to refrain from temporary early treatment during PHI.
format	article
author	Marlous L Grijsen Ferdinand W N M Wit Suzanne Jurriaans Frank P Kroon Emile F Schippers Peter Koopmans Luuk Gras Joep M A Lange Jan M Prins Primo-SHM Study Group
author_facet	Marlous L Grijsen Ferdinand W N M Wit Suzanne Jurriaans Frank P Kroon Emile F Schippers Peter Koopmans Luuk Gras Joep M A Lange Jan M Prins Primo-SHM Study Group
author_sort	Marlous L Grijsen
title	Temporary treatment during primary HIV infection does not affect virologic response to subsequent long-term treatment.
title_short	Temporary treatment during primary HIV infection does not affect virologic response to subsequent long-term treatment.
title_full	Temporary treatment during primary HIV infection does not affect virologic response to subsequent long-term treatment.
title_fullStr	Temporary treatment during primary HIV infection does not affect virologic response to subsequent long-term treatment.
title_full_unstemmed	Temporary treatment during primary HIV infection does not affect virologic response to subsequent long-term treatment.
title_sort	temporary treatment during primary hiv infection does not affect virologic response to subsequent long-term treatment.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/aa29d1b1c52a4b98a97ba1747b59e561
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Temporary treatment during primary HIV infection does not affect virologic response to subsequent long-term treatment.

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