Dynamic sex chromosome expression in Drosophila male germ cells

Sex chromosome gene content and expression is unusual. Here the authors use single cell RNA-Seq on Drosophila larvae to demonstrate that the single X and pair of 4th chromosomes are specifically inactivated in primary spermatocytes, while genes on the single Y chromosome become maximally active in p...

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Autores principales:	Sharvani Mahadevaraju, Justin M. Fear, Miriam Akeju, Brian J. Galletta, Mara M. L. S. Pinheiro, Camila C. Avelino, Diogo C. Cabral-de-Mello, Katie Conlon, Stafania Dell’Orso, Zelalem Demere, Kush Mansuria, Carolina A. Mendonça, Octavio M. Palacios-Gimenez, Eli Ross, Max Savery, Kevin Yu, Harold E. Smith, Vittorio Sartorelli, Haiwang Yang, Nasser M. Rusan, Maria D. Vibranovski, Erika Matunis, Brian Oliver
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aa2d9a1a8070440fbee7c6bcce237801
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spelling	oai:doaj.org-article:aa2d9a1a8070440fbee7c6bcce2378012021-12-02T14:26:44ZDynamic sex chromosome expression in Drosophila male germ cells10.1038/s41467-021-20897-y2041-1723https://doaj.org/article/aa2d9a1a8070440fbee7c6bcce2378012021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-20897-yhttps://doaj.org/toc/2041-1723Sex chromosome gene content and expression is unusual. Here the authors use single cell RNA-Seq on Drosophila larvae to demonstrate that the single X and pair of 4th chromosomes are specifically inactivated in primary spermatocytes, while genes on the single Y chromosome become maximally active in primary spermatocytes.Sharvani MahadevarajuJustin M. FearMiriam AkejuBrian J. GallettaMara M. L. S. PinheiroCamila C. AvelinoDiogo C. Cabral-de-MelloKatie ConlonStafania Dell’OrsoZelalem DemereKush MansuriaCarolina A. MendonçaOctavio M. Palacios-GimenezEli RossMax SaveryKevin YuHarold E. SmithVittorio SartorelliHaiwang YangNasser M. RusanMaria D. VibranovskiErika MatunisBrian OliverNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sharvani Mahadevaraju Justin M. Fear Miriam Akeju Brian J. Galletta Mara M. L. S. Pinheiro Camila C. Avelino Diogo C. Cabral-de-Mello Katie Conlon Stafania Dell’Orso Zelalem Demere Kush Mansuria Carolina A. Mendonça Octavio M. Palacios-Gimenez Eli Ross Max Savery Kevin Yu Harold E. Smith Vittorio Sartorelli Haiwang Yang Nasser M. Rusan Maria D. Vibranovski Erika Matunis Brian Oliver Dynamic sex chromosome expression in Drosophila male germ cells
description	Sex chromosome gene content and expression is unusual. Here the authors use single cell RNA-Seq on Drosophila larvae to demonstrate that the single X and pair of 4th chromosomes are specifically inactivated in primary spermatocytes, while genes on the single Y chromosome become maximally active in primary spermatocytes.
format	article
author	Sharvani Mahadevaraju Justin M. Fear Miriam Akeju Brian J. Galletta Mara M. L. S. Pinheiro Camila C. Avelino Diogo C. Cabral-de-Mello Katie Conlon Stafania Dell’Orso Zelalem Demere Kush Mansuria Carolina A. Mendonça Octavio M. Palacios-Gimenez Eli Ross Max Savery Kevin Yu Harold E. Smith Vittorio Sartorelli Haiwang Yang Nasser M. Rusan Maria D. Vibranovski Erika Matunis Brian Oliver
author_facet	Sharvani Mahadevaraju Justin M. Fear Miriam Akeju Brian J. Galletta Mara M. L. S. Pinheiro Camila C. Avelino Diogo C. Cabral-de-Mello Katie Conlon Stafania Dell’Orso Zelalem Demere Kush Mansuria Carolina A. Mendonça Octavio M. Palacios-Gimenez Eli Ross Max Savery Kevin Yu Harold E. Smith Vittorio Sartorelli Haiwang Yang Nasser M. Rusan Maria D. Vibranovski Erika Matunis Brian Oliver
author_sort	Sharvani Mahadevaraju
title	Dynamic sex chromosome expression in Drosophila male germ cells
title_short	Dynamic sex chromosome expression in Drosophila male germ cells
title_full	Dynamic sex chromosome expression in Drosophila male germ cells
title_fullStr	Dynamic sex chromosome expression in Drosophila male germ cells
title_full_unstemmed	Dynamic sex chromosome expression in Drosophila male germ cells
title_sort	dynamic sex chromosome expression in drosophila male germ cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/aa2d9a1a8070440fbee7c6bcce237801
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Dynamic sex chromosome expression in Drosophila male germ cells

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