A versatile, compartmentalised gut-on-a-chip system for pharmacological and toxicological analyses
Abstract A novel, integrated, in vitro gastrointestinal (GI) system is presented to study oral bioavailability parameters of small molecules. Three compartments were combined into one hyphenated, flow-through set-up. In the first compartment, a compound was exposed dynamically to enzymatic digestion...
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Autores principales: | Pim de Haan, Milou J. C. Santbergen, Meike van der Zande, Hans Bouwmeester, Michel W. F. Nielen, Elisabeth Verpoorte |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/aa2e8b405d444088bfbbdecd824d68f2 |
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