The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins

The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins

The exonuclease Xrn1 mediates crosstalk between transcription and mRNA decay in yeast. Here the authors demonstrate that Xrn1 promotes translation of mRNAs encoding membrane proteins, coupling transcription, translation, and mRNA decay.

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Autores principales: Bernat Blasco-Moreno, Leire de Campos-Mata, René Böttcher, José García-Martínez, Jennifer Jungfleisch, Danny D. Nedialkova, Shiladitya Chattopadhyay, María-Eugenia Gas, Baldomero Oliva, José E. Pérez-Ortín, Sebastian A. Leidel, Mordechai Choder, Juana Díez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Q
Acceso en línea:https://doaj.org/article/aa2f9afce7424f7ba3c5864b73c1260c
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spelling oai:doaj.org-article:aa2f9afce7424f7ba3c5864b73c1260c2021-12-02T16:51:00ZThe exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins10.1038/s41467-019-09199-62041-1723https://doaj.org/article/aa2f9afce7424f7ba3c5864b73c1260c2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09199-6https://doaj.org/toc/2041-1723The exonuclease Xrn1 mediates crosstalk between transcription and mRNA decay in yeast. Here the authors demonstrate that Xrn1 promotes translation of mRNAs encoding membrane proteins, coupling transcription, translation, and mRNA decay.Bernat Blasco-MorenoLeire de Campos-MataRené BöttcherJosé García-MartínezJennifer JungfleischDanny D. NedialkovaShiladitya ChattopadhyayMaría-Eugenia GasBaldomero OlivaJosé E. Pérez-OrtínSebastian A. LeidelMordechai ChoderJuana DíezNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bernat Blasco-Moreno
Leire de Campos-Mata
René Böttcher
José García-Martínez
Jennifer Jungfleisch
Danny D. Nedialkova
Shiladitya Chattopadhyay
María-Eugenia Gas
Baldomero Oliva
José E. Pérez-Ortín
Sebastian A. Leidel
Mordechai Choder
Juana Díez
The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins
description The exonuclease Xrn1 mediates crosstalk between transcription and mRNA decay in yeast. Here the authors demonstrate that Xrn1 promotes translation of mRNAs encoding membrane proteins, coupling transcription, translation, and mRNA decay.
format article
author Bernat Blasco-Moreno
Leire de Campos-Mata
René Böttcher
José García-Martínez
Jennifer Jungfleisch
Danny D. Nedialkova
Shiladitya Chattopadhyay
María-Eugenia Gas
Baldomero Oliva
José E. Pérez-Ortín
Sebastian A. Leidel
Mordechai Choder
Juana Díez
author_facet Bernat Blasco-Moreno
Leire de Campos-Mata
René Böttcher
José García-Martínez
Jennifer Jungfleisch
Danny D. Nedialkova
Shiladitya Chattopadhyay
María-Eugenia Gas
Baldomero Oliva
José E. Pérez-Ortín
Sebastian A. Leidel
Mordechai Choder
Juana Díez
author_sort Bernat Blasco-Moreno
title The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins
title_short The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins
title_full The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins
title_fullStr The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins
title_full_unstemmed The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins
title_sort exonuclease xrn1 activates transcription and translation of mrnas encoding membrane proteins
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/aa2f9afce7424f7ba3c5864b73c1260c
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