A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis

Abstract Herpes simplex virus 1 (HSV-1) is responsible for herpes simplex virus encephalitis (HSE), associated with a 70% mortality rate in the absence of treatment. Despite intravenous treatment with acyclovir, mortality remains significant, highlighting the need for new anti-herpetic agents. Herei...

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Autores principales: Olus Uyar, Pier-Luc Plante, Jocelyne Piret, Marie-Christine Venable, Julie Carbonneau, Jacques Corbeil, Guy Boivin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/aa32d81874b94e47b48bcca576dc80a1
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