Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development
Presynaptic spike timing-dependent long-term depression at hippocampal CA3-CA1 synapses is evident until the third postnatal week in mice. The authors show that maturation beyond four weeks is associated with a switch to long-term potentiation in which astrocytes play a central role.
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Nature Portfolio
2020
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oai:doaj.org-article:aa434e2672a24df5a9babc495514026e2021-12-02T16:38:50ZAstrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development10.1038/s41467-020-18024-42041-1723https://doaj.org/article/aa434e2672a24df5a9babc495514026e2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18024-4https://doaj.org/toc/2041-1723Presynaptic spike timing-dependent long-term depression at hippocampal CA3-CA1 synapses is evident until the third postnatal week in mice. The authors show that maturation beyond four weeks is associated with a switch to long-term potentiation in which astrocytes play a central role.Rafael Falcón-MoyaMikel Pérez-RodríguezJosé Prius-MengualYuniesky Andrade-TalaveraLuis E. Arroyo-GarcíaRocío Pérez-ArtésPedro Mateos-AparicioSónia Guerra-GomesJoão Filipe OliveiraGonzalo FloresAntonio Rodríguez-MorenoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
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DOAJ |
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DOAJ |
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Science Q |
spellingShingle |
Science Q Rafael Falcón-Moya Mikel Pérez-Rodríguez José Prius-Mengual Yuniesky Andrade-Talavera Luis E. Arroyo-García Rocío Pérez-Artés Pedro Mateos-Aparicio Sónia Guerra-Gomes João Filipe Oliveira Gonzalo Flores Antonio Rodríguez-Moreno Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development |
description |
Presynaptic spike timing-dependent long-term depression at hippocampal CA3-CA1 synapses is evident until the third postnatal week in mice. The authors show that maturation beyond four weeks is associated with a switch to long-term potentiation in which astrocytes play a central role. |
format |
article |
author |
Rafael Falcón-Moya Mikel Pérez-Rodríguez José Prius-Mengual Yuniesky Andrade-Talavera Luis E. Arroyo-García Rocío Pérez-Artés Pedro Mateos-Aparicio Sónia Guerra-Gomes João Filipe Oliveira Gonzalo Flores Antonio Rodríguez-Moreno |
author_facet |
Rafael Falcón-Moya Mikel Pérez-Rodríguez José Prius-Mengual Yuniesky Andrade-Talavera Luis E. Arroyo-García Rocío Pérez-Artés Pedro Mateos-Aparicio Sónia Guerra-Gomes João Filipe Oliveira Gonzalo Flores Antonio Rodríguez-Moreno |
author_sort |
Rafael Falcón-Moya |
title |
Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development |
title_short |
Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development |
title_full |
Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development |
title_fullStr |
Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development |
title_full_unstemmed |
Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development |
title_sort |
astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/aa434e2672a24df5a9babc495514026e |
work_keys_str_mv |
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