Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development

Presynaptic spike timing-dependent long-term depression at hippocampal CA3-CA1 synapses is evident until the third postnatal week in mice. The authors show that maturation beyond four weeks is associated with a switch to long-term potentiation in which astrocytes play a central role.

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Autores principales: Rafael Falcón-Moya, Mikel Pérez-Rodríguez, José Prius-Mengual, Yuniesky Andrade-Talavera, Luis E. Arroyo-García, Rocío Pérez-Artés, Pedro Mateos-Aparicio, Sónia Guerra-Gomes, João Filipe Oliveira, Gonzalo Flores, Antonio Rodríguez-Moreno
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/aa434e2672a24df5a9babc495514026e
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spelling oai:doaj.org-article:aa434e2672a24df5a9babc495514026e2021-12-02T16:38:50ZAstrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development10.1038/s41467-020-18024-42041-1723https://doaj.org/article/aa434e2672a24df5a9babc495514026e2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18024-4https://doaj.org/toc/2041-1723Presynaptic spike timing-dependent long-term depression at hippocampal CA3-CA1 synapses is evident until the third postnatal week in mice. The authors show that maturation beyond four weeks is associated with a switch to long-term potentiation in which astrocytes play a central role.Rafael Falcón-MoyaMikel Pérez-RodríguezJosé Prius-MengualYuniesky Andrade-TalaveraLuis E. Arroyo-GarcíaRocío Pérez-ArtésPedro Mateos-AparicioSónia Guerra-GomesJoão Filipe OliveiraGonzalo FloresAntonio Rodríguez-MorenoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Rafael Falcón-Moya
Mikel Pérez-Rodríguez
José Prius-Mengual
Yuniesky Andrade-Talavera
Luis E. Arroyo-García
Rocío Pérez-Artés
Pedro Mateos-Aparicio
Sónia Guerra-Gomes
João Filipe Oliveira
Gonzalo Flores
Antonio Rodríguez-Moreno
Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development
description Presynaptic spike timing-dependent long-term depression at hippocampal CA3-CA1 synapses is evident until the third postnatal week in mice. The authors show that maturation beyond four weeks is associated with a switch to long-term potentiation in which astrocytes play a central role.
format article
author Rafael Falcón-Moya
Mikel Pérez-Rodríguez
José Prius-Mengual
Yuniesky Andrade-Talavera
Luis E. Arroyo-García
Rocío Pérez-Artés
Pedro Mateos-Aparicio
Sónia Guerra-Gomes
João Filipe Oliveira
Gonzalo Flores
Antonio Rodríguez-Moreno
author_facet Rafael Falcón-Moya
Mikel Pérez-Rodríguez
José Prius-Mengual
Yuniesky Andrade-Talavera
Luis E. Arroyo-García
Rocío Pérez-Artés
Pedro Mateos-Aparicio
Sónia Guerra-Gomes
João Filipe Oliveira
Gonzalo Flores
Antonio Rodríguez-Moreno
author_sort Rafael Falcón-Moya
title Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development
title_short Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development
title_full Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development
title_fullStr Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development
title_full_unstemmed Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development
title_sort astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/aa434e2672a24df5a9babc495514026e
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