Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development
Presynaptic spike timing-dependent long-term depression at hippocampal CA3-CA1 synapses is evident until the third postnatal week in mice. The authors show that maturation beyond four weeks is associated with a switch to long-term potentiation in which astrocytes play a central role.
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Autores principales: | Rafael Falcón-Moya, Mikel Pérez-Rodríguez, José Prius-Mengual, Yuniesky Andrade-Talavera, Luis E. Arroyo-García, Rocío Pérez-Artés, Pedro Mateos-Aparicio, Sónia Guerra-Gomes, João Filipe Oliveira, Gonzalo Flores, Antonio Rodríguez-Moreno |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/aa434e2672a24df5a9babc495514026e |
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