Efficacy and dose-dependent safety of intra-arterial delivery of mesenchymal stem cells in a rodent stroke model.

Efficacy and dose-dependent safety of intra-arterial delivery of mesenchymal stem cells in a rodent stroke model.

Intra-arterial (IA) delivery of mesenchymal stem cells (MSCs) for acute ischemic stroke is attractive for clinical translation. However, studies using rat model of stroke have demonstrated that IA MSCs delivery can decrease middle cerebral artery (MCA) flow, which may limit its clinical translation....

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Autores principales: Dileep R Yavagal, Baowan Lin, Ami P Raval, Philip S Garza, Chuanhui Dong, Weizhao Zhao, Erika B Rangel, Ian McNiece, Tatjana Rundek, Ralph L Sacco, Miguel Perez-Pinzon, Joshua M Hare
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/aa4888015b4a4ff6b110e9e41afb9e26
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