The impact of secondhand smoke exposure on the pregnancy outcome: a prospective cohort study among Egyptian community

Abstract Background Secondhand smoke (SHS) exposure gained lesser interest than active smoking. There is evidence from previous studies that SHS exposure had negative effects on fetal growth. This study aimed to examine the effect of smoke exposure on pregnancy outcome and to evaluate the level of n...

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Autores principales:	Eman Sobh, Asmaa Mahmoud Mohammed, Zeinab Adawy, Aziza Hussein Nassef, Adel Hasheesh
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	Cotinine Environmental tobacco smoke Low birth weight Pregnancy outcome Secondhand smoke exposure Diseases of the respiratory system RC705-779 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Acceso en línea:	https://doaj.org/article/aa4af76c420b44fea364d1b524bec751
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spelling	oai:doaj.org-article:aa4af76c420b44fea364d1b524bec7512021-11-07T12:02:33ZThe impact of secondhand smoke exposure on the pregnancy outcome: a prospective cohort study among Egyptian community10.1186/s43168-021-00097-41687-84262314-8551https://doaj.org/article/aa4af76c420b44fea364d1b524bec7512021-11-01T00:00:00Zhttps://doi.org/10.1186/s43168-021-00097-4https://doaj.org/toc/1687-8426https://doaj.org/toc/2314-8551Abstract Background Secondhand smoke (SHS) exposure gained lesser interest than active smoking. There is evidence from previous studies that SHS exposure had negative effects on fetal growth. This study aimed to examine the effect of smoke exposure on pregnancy outcome and to evaluate the level of nicotine urinary end-product cotinine in pregnant women in the late trimester. We included 36 women with a history of SHS exposure and 48 women without a history of exposure; all were in last trimester of pregnancy. We measured cotinine level in urine and followed the two groups until delivery and recorded fetal outcomes. Fetal biophysical parameters and blood flow waveforms were measured using B-mode and Doppler ultrasonography, respectively. Results The total range of the urinary cotinine creatinine ratio (CCR) concentration in the SHS exposed pregnant women was 0.01–0.2, IQR = 0.18 ng/mg.cr, versus 0.01–0.1, and IQR = 0.03 ng/mg.cr in the non-exposed group. The mean value as well as the mean rank of CCR was significantly higher (0.1 ± 0.08 ng/mg.cr., 40.3 respectively) in the exposed pregnant women as compared to the non-exposed pregnant women ((0.04 ± 0.02), 29.3 respectively, p value < 0.05). Newborn of the exposed women had significantly low birth weight which negatively correlated with cotinine level and had a dose-response relationship. Conclusions SHS exposure had negative effects on fetal outcomes. Efforts should be utilized to increase awareness of the consequences of secondhand smoke on the fetus and strict follow-up of exposed women for early detection.Eman SobhAsmaa Mahmoud MohammedZeinab AdawyAziza Hussein NassefAdel HasheeshSpringerOpenarticleCotinineEnvironmental tobacco smokeLow birth weightPregnancy outcomeSecondhand smoke exposureDiseases of the respiratory systemRC705-779Medical emergencies. Critical care. Intensive care. First aidRC86-88.9ENThe Egyptian Journal of Bronchology, Vol 15, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Cotinine Environmental tobacco smoke Low birth weight Pregnancy outcome Secondhand smoke exposure Diseases of the respiratory system RC705-779 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
spellingShingle	Cotinine Environmental tobacco smoke Low birth weight Pregnancy outcome Secondhand smoke exposure Diseases of the respiratory system RC705-779 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9 Eman Sobh Asmaa Mahmoud Mohammed Zeinab Adawy Aziza Hussein Nassef Adel Hasheesh The impact of secondhand smoke exposure on the pregnancy outcome: a prospective cohort study among Egyptian community
description	Abstract Background Secondhand smoke (SHS) exposure gained lesser interest than active smoking. There is evidence from previous studies that SHS exposure had negative effects on fetal growth. This study aimed to examine the effect of smoke exposure on pregnancy outcome and to evaluate the level of nicotine urinary end-product cotinine in pregnant women in the late trimester. We included 36 women with a history of SHS exposure and 48 women without a history of exposure; all were in last trimester of pregnancy. We measured cotinine level in urine and followed the two groups until delivery and recorded fetal outcomes. Fetal biophysical parameters and blood flow waveforms were measured using B-mode and Doppler ultrasonography, respectively. Results The total range of the urinary cotinine creatinine ratio (CCR) concentration in the SHS exposed pregnant women was 0.01–0.2, IQR = 0.18 ng/mg.cr, versus 0.01–0.1, and IQR = 0.03 ng/mg.cr in the non-exposed group. The mean value as well as the mean rank of CCR was significantly higher (0.1 ± 0.08 ng/mg.cr., 40.3 respectively) in the exposed pregnant women as compared to the non-exposed pregnant women ((0.04 ± 0.02), 29.3 respectively, p value < 0.05). Newborn of the exposed women had significantly low birth weight which negatively correlated with cotinine level and had a dose-response relationship. Conclusions SHS exposure had negative effects on fetal outcomes. Efforts should be utilized to increase awareness of the consequences of secondhand smoke on the fetus and strict follow-up of exposed women for early detection.
format	article
author	Eman Sobh Asmaa Mahmoud Mohammed Zeinab Adawy Aziza Hussein Nassef Adel Hasheesh
author_facet	Eman Sobh Asmaa Mahmoud Mohammed Zeinab Adawy Aziza Hussein Nassef Adel Hasheesh
author_sort	Eman Sobh
title	The impact of secondhand smoke exposure on the pregnancy outcome: a prospective cohort study among Egyptian community
title_short	The impact of secondhand smoke exposure on the pregnancy outcome: a prospective cohort study among Egyptian community
title_full	The impact of secondhand smoke exposure on the pregnancy outcome: a prospective cohort study among Egyptian community
title_fullStr	The impact of secondhand smoke exposure on the pregnancy outcome: a prospective cohort study among Egyptian community
title_full_unstemmed	The impact of secondhand smoke exposure on the pregnancy outcome: a prospective cohort study among Egyptian community
title_sort	impact of secondhand smoke exposure on the pregnancy outcome: a prospective cohort study among egyptian community
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/aa4af76c420b44fea364d1b524bec751
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The impact of secondhand smoke exposure on the pregnancy outcome: a prospective cohort study among Egyptian community

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