Bioengineered 3D models of human pancreatic cancer recapitulate in vivo tumour biology

Personalized cancer medicine currently lacks custom platforms that mimic the microenvironment of human tissues. Here, the authors show how self-assembled patient-derived models of pancreatic cancer recapitulate key biological features of the original tumours such as matrix composition and stemness.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: David Osuna de la Peña, Sara Maria David Trabulo, Estelle Collin, Ying Liu, Shreya Sharma, Marianthi Tatari, Diana Behrens, Mert Erkan, Rita T. Lawlor, Aldo Scarpa, Christopher Heeschen, Alvaro Mata, Daniela Loessner
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Q
Accès en ligne:https://doaj.org/article/aa4d680a8e804181b1c4842a522ec5d8
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!