Selenocysteine induces apoptosis in human glioma cells: evidence for TrxR1-targeted inhibition and signaling crosstalk

Selenocysteine induces apoptosis in human glioma cells: evidence for TrxR1-targeted inhibition and signaling crosstalk

Abstract Thioredoxin reductase (TrxR) as a selenium (Se)-containing antioxidase plays key role in regulating intracellular redox status. Selenocystine (SeC) a natural available Se-containing amino acid showed novel anticancer potential through triggering oxidative damage-mediated apoptosis. However,...

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Autores principales: Cun-dong Fan, Xiao-yan Fu, Zong-yong Zhang, Ming-zhi Cao, Jing-yi Sun, Ming-feng Yang, Xiao-ting Fu, Shi-jun Zhao, Lu-rong Shao, Hui-fang Zhang, Xiao-yi Yang, Bao-liang Sun
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/aa5007e439df488c8463e0c4fd458bc4
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