Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation

ESCRT-III complexes assemble in vivo inside membrane structures with a negative Gaussian curvature, but how membrane shape influences ESCRT-III polymerization remains unclear. Here authors use structural and biophysical methods to show how human ESCRT-III polymers assemble on positively curved membr...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Aurélie Bertin, Nicola de Franceschi, Eugenio de la Mora, Sourav Maity, Maryam Alqabandi, Nolwen Miguet, Aurélie di Cicco, Wouter H. Roos, Stéphanie Mangenot, Winfried Weissenhorn, Patricia Bassereau
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aa5a1cbf4c8c4f8ebe1df35bf137441a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:aa5a1cbf4c8c4f8ebe1df35bf137441a
record_format	dspace
spelling	oai:doaj.org-article:aa5a1cbf4c8c4f8ebe1df35bf137441a2021-12-02T15:00:12ZHuman ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation10.1038/s41467-020-16368-52041-1723https://doaj.org/article/aa5a1cbf4c8c4f8ebe1df35bf137441a2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16368-5https://doaj.org/toc/2041-1723ESCRT-III complexes assemble in vivo inside membrane structures with a negative Gaussian curvature, but how membrane shape influences ESCRT-III polymerization remains unclear. Here authors use structural and biophysical methods to show how human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation.Aurélie BertinNicola de FranceschiEugenio de la MoraSourav MaityMaryam AlqabandiNolwen MiguetAurélie di CiccoWouter H. RoosStéphanie MangenotWinfried WeissenhornPatricia BassereauNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aurélie Bertin Nicola de Franceschi Eugenio de la Mora Sourav Maity Maryam Alqabandi Nolwen Miguet Aurélie di Cicco Wouter H. Roos Stéphanie Mangenot Winfried Weissenhorn Patricia Bassereau Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation
description	ESCRT-III complexes assemble in vivo inside membrane structures with a negative Gaussian curvature, but how membrane shape influences ESCRT-III polymerization remains unclear. Here authors use structural and biophysical methods to show how human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation.
format	article
author	Aurélie Bertin Nicola de Franceschi Eugenio de la Mora Sourav Maity Maryam Alqabandi Nolwen Miguet Aurélie di Cicco Wouter H. Roos Stéphanie Mangenot Winfried Weissenhorn Patricia Bassereau
author_facet	Aurélie Bertin Nicola de Franceschi Eugenio de la Mora Sourav Maity Maryam Alqabandi Nolwen Miguet Aurélie di Cicco Wouter H. Roos Stéphanie Mangenot Winfried Weissenhorn Patricia Bassereau
author_sort	Aurélie Bertin
title	Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation
title_short	Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation
title_full	Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation
title_fullStr	Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation
title_full_unstemmed	Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation
title_sort	human escrt-iii polymers assemble on positively curved membranes and induce helical membrane tube formation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/aa5a1cbf4c8c4f8ebe1df35bf137441a
work_keys_str_mv	AT aureliebertin humanescrtiiipolymersassembleonpositivelycurvedmembranesandinducehelicalmembranetubeformation AT nicoladefranceschi humanescrtiiipolymersassembleonpositivelycurvedmembranesandinducehelicalmembranetubeformation AT eugeniodelamora humanescrtiiipolymersassembleonpositivelycurvedmembranesandinducehelicalmembranetubeformation AT souravmaity humanescrtiiipolymersassembleonpositivelycurvedmembranesandinducehelicalmembranetubeformation AT maryamalqabandi humanescrtiiipolymersassembleonpositivelycurvedmembranesandinducehelicalmembranetubeformation AT nolwenmiguet humanescrtiiipolymersassembleonpositivelycurvedmembranesandinducehelicalmembranetubeformation AT aureliedicicco humanescrtiiipolymersassembleonpositivelycurvedmembranesandinducehelicalmembranetubeformation AT wouterhroos humanescrtiiipolymersassembleonpositivelycurvedmembranesandinducehelicalmembranetubeformation AT stephaniemangenot humanescrtiiipolymersassembleonpositivelycurvedmembranesandinducehelicalmembranetubeformation AT winfriedweissenhorn humanescrtiiipolymersassembleonpositivelycurvedmembranesandinducehelicalmembranetubeformation AT patriciabassereau humanescrtiiipolymersassembleonpositivelycurvedmembranesandinducehelicalmembranetubeformation
_version_	1718389222934577152

Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation

Ejemplares similares