Spatial organization of FcγR and TLR2/1 on phagosome membranes differentially regulates their synergistic and inhibitory receptor crosstalk
Abstract Many innate immune receptors function collaboratively to detect and elicit immune responses to pathogens, but the physical mechanisms that govern the interaction and signaling crosstalk between the receptors are unclear. In this study, we report that the signaling crosstalk between Fc gamma...
Guardado en:
Autores principales: | Wenqian Li, Miao Li, Stephen M. Anthony, Yan Yu |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/aa5bd7ea66714a3a84902a35830488ff |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Fc γ receptor IIIB (FcγRIIIB) polymorphisms are associated with clinical malaria in Ghanaian children.
por: Bright Adu, et al.
Publicado: (2012) -
Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia
por: Björn Rissiek, et al.
Publicado: (2017) -
FcγRIIb differentially regulates pre-immune and germinal center B cell tolerance in mouse and human
por: Marion Espéli, et al.
Publicado: (2019) -
Optimization of 4-1BB antibody for cancer immunotherapy by balancing agonistic strength with FcγR affinity
por: Xinyue Qi, et al.
Publicado: (2019) -
Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
por: Gaoqian Feng, et al.
Publicado: (2021)