Glibenclamide does not improve outcome following severe collagenase-induced intracerebral hemorrhage in rats.
Intracerebral hemorrhage (ICH) is a devastating insult with few effective treatments. Edema and raised intracranial pressure contribute to poor outcome after ICH. Glibenclamide blocks the sulfonylurea 1 transient receptor potential melastatin 4 (Sur1-Trpm4) channel implicated in edema formation. Whi...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/aa5fe3b5564147809f58863890600c95 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|