Enantiodivergence by minimal modification of an acyclic chiral secondary aminocatalyst

Enantiodivergent methods, which to access both enantiomers of the same compound, are of importance in drug synthesis. Here, the authors show that by simply changing a NiBu- to a NMe-group in readily available amine organocatalysts, high stereocontrol and broad scope are achieved in eight asymmetric...

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Autores principales: Jun Dai, Zhuang Wang, Yuhua Deng, Lei Zhu, Fangzhi Peng, Yu Lan, Zhihui Shao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/aa64014d1ebc414ba5b6bfcaf4d115fe
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