Mice lacking PLAP-1/asporin counteracts high fat diet-induced metabolic disorder and alveolar bone loss by controlling adipose tissue expansion

Abstract Adipose tissue fibrosis with chronic inflammation is a hallmark of obesity-related metabolic disorders, and the role of proteoglycans in developing adipose tissue fibrosis is of interest. Periodontal disease is associated with obesity; however, the underlying molecular mechanisms remain unc...

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Bibliographic Details
Main Authors: Hiromi Sakashita, Satoru Yamada, Masaki Kinoshita, Tetsuhiro Kajikawa, Tomoaki Iwayama, Shinya Murakami
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
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Online Access:https://doaj.org/article/aa65137dca8f4a19b0f00e595a02854e
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