Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage
One of the challenges of synthetic self-assembled capsules is achieving selective recognition of specific cargoes. Here, authors synthesize a self-assembled porphyrin cubic cage that is capable of sequestering imidazole and thiazole-containing small molecules and peptides, protecting them from prote...
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Nature Portfolio
2017
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oai:doaj.org-article:aa6b5f198c7d4869a569764651de33d12021-12-02T15:37:00ZSequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage10.1038/ncomms148822041-1723https://doaj.org/article/aa6b5f198c7d4869a569764651de33d12017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14882https://doaj.org/toc/2041-1723One of the challenges of synthetic self-assembled capsules is achieving selective recognition of specific cargoes. Here, authors synthesize a self-assembled porphyrin cubic cage that is capable of sequestering imidazole and thiazole-containing small molecules and peptides, protecting them from proteolysis.Jesús MosqueraBartosz SzyszkoSarah K. Y. HoJonathan R. NitschkeNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-6 (2017) |
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Science Q Jesús Mosquera Bartosz Szyszko Sarah K. Y. Ho Jonathan R. Nitschke Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage |
description |
One of the challenges of synthetic self-assembled capsules is achieving selective recognition of specific cargoes. Here, authors synthesize a self-assembled porphyrin cubic cage that is capable of sequestering imidazole and thiazole-containing small molecules and peptides, protecting them from proteolysis. |
format |
article |
author |
Jesús Mosquera Bartosz Szyszko Sarah K. Y. Ho Jonathan R. Nitschke |
author_facet |
Jesús Mosquera Bartosz Szyszko Sarah K. Y. Ho Jonathan R. Nitschke |
author_sort |
Jesús Mosquera |
title |
Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage |
title_short |
Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage |
title_full |
Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage |
title_fullStr |
Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage |
title_full_unstemmed |
Sequence-selective encapsulation and protection of long peptides by a self-assembled FeII8L6 cubic cage |
title_sort |
sequence-selective encapsulation and protection of long peptides by a self-assembled feii8l6 cubic cage |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/aa6b5f198c7d4869a569764651de33d1 |
work_keys_str_mv |
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