COVID-19 and SARS-CoV-2: Everything we know so far – A comprehensive review

Coronavirus disease-2019 (COVID-19) emerged as a unique type of pneumonia outbreak in the Wuhan city of China in 2019 and spread to all its provinces in a matter of days and then to every continent of the world except Antarctica within 3–4 month. This paper aims to comprehensively consolidate the av...

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Autores principales:	Naz Sumaira, Zahoor Muhammad, Sahibzada Muhammad Umar Khayam, Ullah Riaz, Alqahtani Ali S.
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	covid-19 sars-cov-2 genome epidemiology risk factors and transmission of covid-19 pathogenesis and clinical features of covid-19 diagnosis treatment and vaccine of covid-19 prevention and mitigation of covid-19 reinfection with covid-19 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/aa6c74a8bed744cabb88cfb573e8fc1a
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spelling	oai:doaj.org-article:aa6c74a8bed744cabb88cfb573e8fc1a2021-12-05T14:10:44ZCOVID-19 and SARS-CoV-2: Everything we know so far – A comprehensive review2391-542010.1515/chem-2021-0049https://doaj.org/article/aa6c74a8bed744cabb88cfb573e8fc1a2021-05-01T00:00:00Zhttps://doi.org/10.1515/chem-2021-0049https://doaj.org/toc/2391-5420Coronavirus disease-2019 (COVID-19) emerged as a unique type of pneumonia outbreak in the Wuhan city of China in 2019 and spread to all its provinces in a matter of days and then to every continent of the world except Antarctica within 3–4 month. This paper aims to comprehensively consolidate the available information about COVID-19 and present all the possible information about this disease in form of a single paper to readers. Unparalleled research and exhaustive studies of everything about the disease and its causative virus, i.e., severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are underway since its emergence. The genome sequence of the virus was made available within a record short time by China, making possible immediate study of its structure and characteristics. The routes of transmission of the disease, signs and symptoms, incubation period, pathogenesis, and pathophysiology have been extensively studied and presented in an organized way in this review paper. The number of confirmed cases and case fatality and mortality rates are updated regularly. The different diagnostic mechanisms have been characterized. Testing and management criteria and protocols have been adopted. Extensive efforts are underway for finding a treatment of the disease and developing a vaccine against it. A number of vaccines are available even in markets in different countries. More and more ways of personal protection, prevention, and mitigation of the disease are being explored and shared. While the outbreak has been declared as pandemic, the response of scientists was timely and enormous; thousands of publications about various aspects and impact of the diseases and its causative virus are there on the World Health Organization database and many more studies are underway. The purpose of writing this review article is to provide a comprehensive summary of the major aspects and important scientific findings so far, about COVID-19 and SARS-CoV-2, in a single article for ready reference.Naz SumairaZahoor MuhammadSahibzada Muhammad Umar KhayamUllah RiazAlqahtani Ali S.De Gruyterarticlecovid-19sars-cov-2 genomeepidemiologyrisk factors and transmission of covid-19pathogenesis and clinical features of covid-19diagnosistreatmentand vaccine of covid-19prevention and mitigation of covid-19reinfection with covid-19ChemistryQD1-999ENOpen Chemistry, Vol 19, Iss 1, Pp 548-575 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	covid-19 sars-cov-2 genome epidemiology risk factors and transmission of covid-19 pathogenesis and clinical features of covid-19 diagnosis treatment and vaccine of covid-19 prevention and mitigation of covid-19 reinfection with covid-19 Chemistry QD1-999
spellingShingle	covid-19 sars-cov-2 genome epidemiology risk factors and transmission of covid-19 pathogenesis and clinical features of covid-19 diagnosis treatment and vaccine of covid-19 prevention and mitigation of covid-19 reinfection with covid-19 Chemistry QD1-999 Naz Sumaira Zahoor Muhammad Sahibzada Muhammad Umar Khayam Ullah Riaz Alqahtani Ali S. COVID-19 and SARS-CoV-2: Everything we know so far – A comprehensive review
description	Coronavirus disease-2019 (COVID-19) emerged as a unique type of pneumonia outbreak in the Wuhan city of China in 2019 and spread to all its provinces in a matter of days and then to every continent of the world except Antarctica within 3–4 month. This paper aims to comprehensively consolidate the available information about COVID-19 and present all the possible information about this disease in form of a single paper to readers. Unparalleled research and exhaustive studies of everything about the disease and its causative virus, i.e., severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are underway since its emergence. The genome sequence of the virus was made available within a record short time by China, making possible immediate study of its structure and characteristics. The routes of transmission of the disease, signs and symptoms, incubation period, pathogenesis, and pathophysiology have been extensively studied and presented in an organized way in this review paper. The number of confirmed cases and case fatality and mortality rates are updated regularly. The different diagnostic mechanisms have been characterized. Testing and management criteria and protocols have been adopted. Extensive efforts are underway for finding a treatment of the disease and developing a vaccine against it. A number of vaccines are available even in markets in different countries. More and more ways of personal protection, prevention, and mitigation of the disease are being explored and shared. While the outbreak has been declared as pandemic, the response of scientists was timely and enormous; thousands of publications about various aspects and impact of the diseases and its causative virus are there on the World Health Organization database and many more studies are underway. The purpose of writing this review article is to provide a comprehensive summary of the major aspects and important scientific findings so far, about COVID-19 and SARS-CoV-2, in a single article for ready reference.
format	article
author	Naz Sumaira Zahoor Muhammad Sahibzada Muhammad Umar Khayam Ullah Riaz Alqahtani Ali S.
author_facet	Naz Sumaira Zahoor Muhammad Sahibzada Muhammad Umar Khayam Ullah Riaz Alqahtani Ali S.
author_sort	Naz Sumaira
title	COVID-19 and SARS-CoV-2: Everything we know so far – A comprehensive review
title_short	COVID-19 and SARS-CoV-2: Everything we know so far – A comprehensive review
title_full	COVID-19 and SARS-CoV-2: Everything we know so far – A comprehensive review
title_fullStr	COVID-19 and SARS-CoV-2: Everything we know so far – A comprehensive review
title_full_unstemmed	COVID-19 and SARS-CoV-2: Everything we know so far – A comprehensive review
title_sort	covid-19 and sars-cov-2: everything we know so far – a comprehensive review
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/aa6c74a8bed744cabb88cfb573e8fc1a
work_keys_str_mv	AT nazsumaira covid19andsarscov2everythingweknowsofaracomprehensivereview AT zahoormuhammad covid19andsarscov2everythingweknowsofaracomprehensivereview AT sahibzadamuhammadumarkhayam covid19andsarscov2everythingweknowsofaracomprehensivereview AT ullahriaz covid19andsarscov2everythingweknowsofaracomprehensivereview AT alqahtanialis covid19andsarscov2everythingweknowsofaracomprehensivereview
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COVID-19 and SARS-CoV-2: Everything we know so far – A comprehensive review

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