Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus

During cell migration, cells are polarized with distinct front vs. rear regions but whether and how polarity is transmitted to the nucleus is unclear. Here the authors show that frontally-biased endoplasmic reticulum and the nuclear membrane protein Emerin contribute to front-rear nuclear cell polar...

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Autores principales:	Paulina Nastały, Divya Purushothaman, Stefano Marchesi, Alessandro Poli, Tobias Lendenmann, Gururaj Rao Kidiyoor, Galina V. Beznoussenko, Stefania Lavore, Orso Maria Romano, Dimos Poulikakos, Marco Cosentino Lagomarsino, Alexander A. Mironov, Aldo Ferrari, Paolo Maiuri
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aa70ea3edc634f5f887c9193f5d91f4f
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spelling	oai:doaj.org-article:aa70ea3edc634f5f887c9193f5d91f4f2021-12-02T14:40:27ZRole of the nuclear membrane protein Emerin in front-rear polarity of the nucleus10.1038/s41467-020-15910-92041-1723https://doaj.org/article/aa70ea3edc634f5f887c9193f5d91f4f2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15910-9https://doaj.org/toc/2041-1723During cell migration, cells are polarized with distinct front vs. rear regions but whether and how polarity is transmitted to the nucleus is unclear. Here the authors show that frontally-biased endoplasmic reticulum and the nuclear membrane protein Emerin contribute to front-rear nuclear cell polarity.Paulina NastałyDivya PurushothamanStefano MarchesiAlessandro PoliTobias LendenmannGururaj Rao KidiyoorGalina V. BeznoussenkoStefania LavoreOrso Maria RomanoDimos PoulikakosMarco Cosentino LagomarsinoAlexander A. MironovAldo FerrariPaolo MaiuriNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Paulina Nastały Divya Purushothaman Stefano Marchesi Alessandro Poli Tobias Lendenmann Gururaj Rao Kidiyoor Galina V. Beznoussenko Stefania Lavore Orso Maria Romano Dimos Poulikakos Marco Cosentino Lagomarsino Alexander A. Mironov Aldo Ferrari Paolo Maiuri Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus
description	During cell migration, cells are polarized with distinct front vs. rear regions but whether and how polarity is transmitted to the nucleus is unclear. Here the authors show that frontally-biased endoplasmic reticulum and the nuclear membrane protein Emerin contribute to front-rear nuclear cell polarity.
format	article
author	Paulina Nastały Divya Purushothaman Stefano Marchesi Alessandro Poli Tobias Lendenmann Gururaj Rao Kidiyoor Galina V. Beznoussenko Stefania Lavore Orso Maria Romano Dimos Poulikakos Marco Cosentino Lagomarsino Alexander A. Mironov Aldo Ferrari Paolo Maiuri
author_facet	Paulina Nastały Divya Purushothaman Stefano Marchesi Alessandro Poli Tobias Lendenmann Gururaj Rao Kidiyoor Galina V. Beznoussenko Stefania Lavore Orso Maria Romano Dimos Poulikakos Marco Cosentino Lagomarsino Alexander A. Mironov Aldo Ferrari Paolo Maiuri
author_sort	Paulina Nastały
title	Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus
title_short	Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus
title_full	Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus
title_fullStr	Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus
title_full_unstemmed	Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus
title_sort	role of the nuclear membrane protein emerin in front-rear polarity of the nucleus
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/aa70ea3edc634f5f887c9193f5d91f4f
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Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus

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