Transcription organizes euchromatin via microphase separation

How euchromatin organisation and transcription are related is unclear. Here, the authors observe the dynamics of euchromatin organization showing that accumulating RNA recruits RNA-binding proteins that together with transcribed euchromatin separate from non-transcribed euchromatin, forming micropha...

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Autores principales:	Lennart Hilbert, Yuko Sato, Ksenia Kuznetsova, Tommaso Bianucci, Hiroshi Kimura, Frank Jülicher, Alf Honigmann, Vasily Zaburdaev, Nadine L. Vastenhouw
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aa75548e2a9c4e8cbdb689ee3ea5a16d
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spelling	oai:doaj.org-article:aa75548e2a9c4e8cbdb689ee3ea5a16d2021-12-02T13:33:01ZTranscription organizes euchromatin via microphase separation10.1038/s41467-021-21589-32041-1723https://doaj.org/article/aa75548e2a9c4e8cbdb689ee3ea5a16d2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21589-3https://doaj.org/toc/2041-1723How euchromatin organisation and transcription are related is unclear. Here, the authors observe the dynamics of euchromatin organization showing that accumulating RNA recruits RNA-binding proteins that together with transcribed euchromatin separate from non-transcribed euchromatin, forming microphases.Lennart HilbertYuko SatoKsenia KuznetsovaTommaso BianucciHiroshi KimuraFrank JülicherAlf HonigmannVasily ZaburdaevNadine L. VastenhouwNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lennart Hilbert Yuko Sato Ksenia Kuznetsova Tommaso Bianucci Hiroshi Kimura Frank Jülicher Alf Honigmann Vasily Zaburdaev Nadine L. Vastenhouw Transcription organizes euchromatin via microphase separation
description	How euchromatin organisation and transcription are related is unclear. Here, the authors observe the dynamics of euchromatin organization showing that accumulating RNA recruits RNA-binding proteins that together with transcribed euchromatin separate from non-transcribed euchromatin, forming microphases.
format	article
author	Lennart Hilbert Yuko Sato Ksenia Kuznetsova Tommaso Bianucci Hiroshi Kimura Frank Jülicher Alf Honigmann Vasily Zaburdaev Nadine L. Vastenhouw
author_facet	Lennart Hilbert Yuko Sato Ksenia Kuznetsova Tommaso Bianucci Hiroshi Kimura Frank Jülicher Alf Honigmann Vasily Zaburdaev Nadine L. Vastenhouw
author_sort	Lennart Hilbert
title	Transcription organizes euchromatin via microphase separation
title_short	Transcription organizes euchromatin via microphase separation
title_full	Transcription organizes euchromatin via microphase separation
title_fullStr	Transcription organizes euchromatin via microphase separation
title_full_unstemmed	Transcription organizes euchromatin via microphase separation
title_sort	transcription organizes euchromatin via microphase separation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/aa75548e2a9c4e8cbdb689ee3ea5a16d
work_keys_str_mv	AT lennarthilbert transcriptionorganizeseuchromatinviamicrophaseseparation AT yukosato transcriptionorganizeseuchromatinviamicrophaseseparation AT kseniakuznetsova transcriptionorganizeseuchromatinviamicrophaseseparation AT tommasobianucci transcriptionorganizeseuchromatinviamicrophaseseparation AT hiroshikimura transcriptionorganizeseuchromatinviamicrophaseseparation AT frankjulicher transcriptionorganizeseuchromatinviamicrophaseseparation AT alfhonigmann transcriptionorganizeseuchromatinviamicrophaseseparation AT vasilyzaburdaev transcriptionorganizeseuchromatinviamicrophaseseparation AT nadinelvastenhouw transcriptionorganizeseuchromatinviamicrophaseseparation
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Transcription organizes euchromatin via microphase separation

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