The role of optical coherence tomography and other intravascular imaging modalities in cardiac allograft vasculopathy

Orthotopic heart transplantation (OHT) is the standard-of-care for end-stage heart disease. Although a significant improvement in the prognosis of patients after OHT has been observed in recent years, their overall mortality remains relatively high, with a median survival of approximately 10 years a...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Maciej Dyrbuś, Mariusz Gąsior, Bożena Szyguła-Jurkiewicz, Piotr Przybyłowski
Formato:	article
Lenguaje:	EN
Publicado:	Termedia Publishing House 2020
Materias:	cardiac allograft vasculopathy heart transplantation intravascular imaging optical coherence tomography Medicine R
Acceso en línea:	https://doaj.org/article/aa80a1d77e5e412eaa718fb4ddf9acd1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:aa80a1d77e5e412eaa718fb4ddf9acd1
record_format	dspace
spelling	oai:doaj.org-article:aa80a1d77e5e412eaa718fb4ddf9acd12021-12-02T18:55:08ZThe role of optical coherence tomography and other intravascular imaging modalities in cardiac allograft vasculopathy1734-93381897-429510.5114/aic.2020.93909https://doaj.org/article/aa80a1d77e5e412eaa718fb4ddf9acd12020-04-01T00:00:00Zhttps://www.termedia.pl/The-role-of-optical-coherence-tomography-and-other-intravascular-imaging-modalities-in-cardiac-allograft-vasculopathy,35,40161,1,1.htmlhttps://doaj.org/toc/1734-9338https://doaj.org/toc/1897-4295Orthotopic heart transplantation (OHT) is the standard-of-care for end-stage heart disease. Although a significant improvement in the prognosis of patients after OHT has been observed in recent years, their overall mortality remains relatively high, with a median survival of approximately 10 years after transplantation. One of the primary causes of death in patients after OHT is cardiac allograft vasculopathy (CAV), the condition developing specifically in the coronary vasculature after OHT, the pathophysiology of which is still inadequately known. It is estimated that CAV development and progression is responsible for approximately 30% of deaths within five years post-OHT. According to the International Society for Heart and Lung Transplantation (ISHLT) Nomenclature for CAV, its presence should be assessed primarily by the coronary angiography performed routinely after OHT, mostly due to its wide availability, reproducibility, and low complication rate. However, the analysis of CAV in coronary angiography has limitations, mostly concerning its – sometimes inadequate – sensitivity and specificity. Hence, there is a growing need for the introduction of more accurate methods of CAV assessment, such as intravascular imaging, which through a thorough evaluation of the arterial wall structure and thickness allows the drawbacks of routine angiography to be minimised. The aim of the article was to critically summarise the current findings derived from the analysis of CAV by optical coherence tomography, the other intravascular imaging modalities, such as intravascular ultrasound (IVUS) and IVUS-derived virtual histology, along with physiological assessment with the use of the fractional flow reserve.Maciej DyrbuśMariusz GąsiorBożena Szyguła-JurkiewiczPiotr PrzybyłowskiTermedia Publishing Housearticlecardiac allograft vasculopathy heart transplantation intravascular imaging optical coherence tomographyMedicineRENAdvances in Interventional Cardiology, Vol 16, Iss 1, Pp 19-29 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiac allograft vasculopathy heart transplantation intravascular imaging optical coherence tomography Medicine R
spellingShingle	cardiac allograft vasculopathy heart transplantation intravascular imaging optical coherence tomography Medicine R Maciej Dyrbuś Mariusz Gąsior Bożena Szyguła-Jurkiewicz Piotr Przybyłowski The role of optical coherence tomography and other intravascular imaging modalities in cardiac allograft vasculopathy
description	Orthotopic heart transplantation (OHT) is the standard-of-care for end-stage heart disease. Although a significant improvement in the prognosis of patients after OHT has been observed in recent years, their overall mortality remains relatively high, with a median survival of approximately 10 years after transplantation. One of the primary causes of death in patients after OHT is cardiac allograft vasculopathy (CAV), the condition developing specifically in the coronary vasculature after OHT, the pathophysiology of which is still inadequately known. It is estimated that CAV development and progression is responsible for approximately 30% of deaths within five years post-OHT. According to the International Society for Heart and Lung Transplantation (ISHLT) Nomenclature for CAV, its presence should be assessed primarily by the coronary angiography performed routinely after OHT, mostly due to its wide availability, reproducibility, and low complication rate. However, the analysis of CAV in coronary angiography has limitations, mostly concerning its – sometimes inadequate – sensitivity and specificity. Hence, there is a growing need for the introduction of more accurate methods of CAV assessment, such as intravascular imaging, which through a thorough evaluation of the arterial wall structure and thickness allows the drawbacks of routine angiography to be minimised. The aim of the article was to critically summarise the current findings derived from the analysis of CAV by optical coherence tomography, the other intravascular imaging modalities, such as intravascular ultrasound (IVUS) and IVUS-derived virtual histology, along with physiological assessment with the use of the fractional flow reserve.
format	article
author	Maciej Dyrbuś Mariusz Gąsior Bożena Szyguła-Jurkiewicz Piotr Przybyłowski
author_facet	Maciej Dyrbuś Mariusz Gąsior Bożena Szyguła-Jurkiewicz Piotr Przybyłowski
author_sort	Maciej Dyrbuś
title	The role of optical coherence tomography and other intravascular imaging modalities in cardiac allograft vasculopathy
title_short	The role of optical coherence tomography and other intravascular imaging modalities in cardiac allograft vasculopathy
title_full	The role of optical coherence tomography and other intravascular imaging modalities in cardiac allograft vasculopathy
title_fullStr	The role of optical coherence tomography and other intravascular imaging modalities in cardiac allograft vasculopathy
title_full_unstemmed	The role of optical coherence tomography and other intravascular imaging modalities in cardiac allograft vasculopathy
title_sort	role of optical coherence tomography and other intravascular imaging modalities in cardiac allograft vasculopathy
publisher	Termedia Publishing House
publishDate	2020
url	https://doaj.org/article/aa80a1d77e5e412eaa718fb4ddf9acd1
work_keys_str_mv	AT maciejdyrbus theroleofopticalcoherencetomographyandotherintravascularimagingmodalitiesincardiacallograftvasculopathy AT mariuszgasior theroleofopticalcoherencetomographyandotherintravascularimagingmodalitiesincardiacallograftvasculopathy AT bozenaszygułajurkiewicz theroleofopticalcoherencetomographyandotherintravascularimagingmodalitiesincardiacallograftvasculopathy AT piotrprzybyłowski theroleofopticalcoherencetomographyandotherintravascularimagingmodalitiesincardiacallograftvasculopathy AT maciejdyrbus roleofopticalcoherencetomographyandotherintravascularimagingmodalitiesincardiacallograftvasculopathy AT mariuszgasior roleofopticalcoherencetomographyandotherintravascularimagingmodalitiesincardiacallograftvasculopathy AT bozenaszygułajurkiewicz roleofopticalcoherencetomographyandotherintravascularimagingmodalitiesincardiacallograftvasculopathy AT piotrprzybyłowski roleofopticalcoherencetomographyandotherintravascularimagingmodalitiesincardiacallograftvasculopathy
_version_	1718377287733215232

The role of optical coherence tomography and other intravascular imaging modalities in cardiac allograft vasculopathy

Ejemplares similares